War of the Microbial Worlds

Ruqaiyyah Siddiqui, Ibne Karim M. Ali, Jennifer R. Cope, Naveed Ahmed Khan

Research output: Book/ReportBook


N. fowleri harbours microbial organisms including viruses, and bacteria, some of which are potential pathogens. The precise nature of this symbiosis is not clear, but it is suggested that such interactions enable pathogenic microbes to survive hostile conditions and this association can lead to their transmission to susceptible hosts to establish infection. In this context, Naegleria can act as vehicles for the multiplication and dispersal of pathogenic microbes as well as providing shelter for such bacteria from antibiotic and disinfection treatments. These findings suggest that employing anti-amoebic approaches in eradicating bacterial pathogens may be an effective strategy to counter threat from both Naegleria as well as bacterial pathogens. For example, Naegleria-Legionella interactions have gained significant attention by the scientific and the medical community.
Original languageEnglish
Place of PublicationNorfolk, UK
PublisherCaister Academic Press
Number of pages9
ISBN (Electronic)9781910190548
ISBN (Print)9781910190531
Publication statusPublished - Jun 2016

Publication series

NameBrain-eating Amoebae: Biology and Pathogenesis of Naegleria fowleri
PublisherCaister Academic Press


  • Amoebida
  • Amœbida
  • Central Nervous System Diseases
  • Central Nervous System Protozoal Infections
  • Central nervous system Diseases
  • Naegleria
  • Naegleria fowleri
  • SCIENCE Life Sciences Biology
  • SCIENCE Life Sciences Microbiology
  • Système nerveux central Maladies


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