Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression

Lubna Abu Zohair; Hind Zantout; Marta Vallejo; Md Azher Uddin

doi:10.1609/aaaiss.v6i1.36033

Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression

Lubna Abu Zohair^*, Hind Zantout, Marta Vallejo, Md Azher Uddin

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This study explores the potential of advanced, context-aware machine learning algorithms, such as autoencoders, to represent longitudinal cerebrospinal fluid proteomic data, enabling the objective discovery of two patient strata with significance.

Original language	English
Title of host publication	Proceedings of the 2025 AAAI Summer Symposium Series
Editors	Christopher W. Geib, Ron Petrick, Abrar Ullah
Place of Publication	Dubai, UAE
Publisher	AAAI Press
Pages	72-74
Number of pages	3
Volume	6
Edition	1
ISBN (Print)	1577358996, 9781577358992
DOIs	https://doi.org/10.1609/aaaiss.v6i1.36033
Publication status	Published - 1 Aug 2025
Event	AAAI 2025 Summer Symposium: Context-Awareness in Cyber-Physical Systems - Heriot-Watt University Dubai, Dubai, United Arab Emirates Duration: 20 May 2025 → 22 May 2025 https://sites.google.com/view/cyber-physical-systems https://haic2025.com/

Publication series

Name	AAAI Summer Symposium Series (SuSS)
Publisher	AAAI
Number	1
Volume	6
ISSN (Print)	2994-4317

Conference

Conference	AAAI 2025 Summer Symposium
Country/Territory	United Arab Emirates
City	Dubai
Period	20/05/25 → 22/05/25
Internet address	https://sites.google.com/view/cyber-physical-systems https://haic2025.com/

Access to Document

10.1609/aaaiss.v6i1.36033

https://ojs.aaai.org/index.php/AAAI-SS/article/view/36033/38188

Cite this

Abu Zohair, L., Zantout, H., Vallejo, M., & Uddin, M. A. (2025). Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression. In C. W. Geib, R. Petrick, & A. Ullah (Eds.), Proceedings of the 2025 AAAI Summer Symposium Series (1 ed., Vol. 6, pp. 72-74). (AAAI Summer Symposium Series (SuSS); Vol. 6, No. 1). AAAI Press. https://doi.org/10.1609/aaaiss.v6i1.36033

Abu Zohair, Lubna ; Zantout, Hind ; Vallejo, Marta et al. / Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression. Proceedings of the 2025 AAAI Summer Symposium Series. editor / Christopher W. Geib ; Ron Petrick ; Abrar Ullah. Vol. 6 1. ed. Dubai, UAE : AAAI Press, 2025. pp. 72-74 (AAAI Summer Symposium Series (SuSS); 1).

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title = "Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson{\textquoteright}s Disease Progression",

abstract = "This study explores the potential of advanced, context-aware machine learning algorithms, such as autoencoders, to represent longitudinal cerebrospinal fluid proteomic data, enabling the objective discovery of two patient strata with significance.",

author = "\{Abu Zohair\}, Lubna and Hind Zantout and Marta Vallejo and Uddin, \{Md Azher\}",

year = "2025",

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doi = "10.1609/aaaiss.v6i1.36033",

language = "English",

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volume = "6",

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publisher = "AAAI Press",

number = "1",

pages = "72--74",

editor = "Geib, \{Christopher W.\} and Ron Petrick and Abrar Ullah",

booktitle = "Proceedings of the 2025 AAAI Summer Symposium Series",

edition = "1",

note = "AAAI 2025 Summer Symposium : Context-Awareness in Cyber-Physical Systems ; Conference date: 20-05-2025 Through 22-05-2025",

url = "https://sites.google.com/view/cyber-physical-systems, https://haic2025.com/",

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Abu Zohair, L, Zantout, H , Vallejo, M & Uddin, MA 2025, Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression. in CW Geib, R Petrick & A Ullah (eds), Proceedings of the 2025 AAAI Summer Symposium Series. 1 edn, vol. 6, AAAI Summer Symposium Series (SuSS), no. 1, vol. 6, AAAI Press, Dubai, UAE, pp. 72-74, AAAI 2025 Summer Symposium, Dubai, United Arab Emirates, 20/05/25. https://doi.org/10.1609/aaaiss.v6i1.36033

Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression. / Abu Zohair, Lubna; Zantout, Hind ; Vallejo, Marta et al.
Proceedings of the 2025 AAAI Summer Symposium Series. ed. / Christopher W. Geib; Ron Petrick; Abrar Ullah. Vol. 6 1. ed. Dubai, UAE: AAAI Press, 2025. p. 72-74 (AAAI Summer Symposium Series (SuSS); Vol. 6, No. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression

AU - Abu Zohair, Lubna

AU - Zantout, Hind

AU - Vallejo, Marta

AU - Uddin, Md Azher

PY - 2025/8/1

Y1 - 2025/8/1

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AB - This study explores the potential of advanced, context-aware machine learning algorithms, such as autoencoders, to represent longitudinal cerebrospinal fluid proteomic data, enabling the objective discovery of two patient strata with significance.

U2 - 10.1609/aaaiss.v6i1.36033

DO - 10.1609/aaaiss.v6i1.36033

M3 - Conference contribution

SN - 1577358996

SN - 9781577358992

VL - 6

T3 - AAAI Summer Symposium Series (SuSS)

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BT - Proceedings of the 2025 AAAI Summer Symposium Series

A2 - Geib, Christopher W.

A2 - Petrick, Ron

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PB - AAAI Press

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T2 - AAAI 2025 Summer Symposium

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Abu Zohair L, Zantout H , Vallejo M , Uddin MA. Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression. In Geib CW, Petrick R, Ullah A, editors, Proceedings of the 2025 AAAI Summer Symposium Series. 1 ed. Vol. 6. Dubai, UAE: AAAI Press. 2025. p. 72-74. (AAAI Summer Symposium Series (SuSS); 1). doi: 10.1609/aaaiss.v6i1.36033

Unsupervised Machine Learning Using Cerebrospinal Fluid Proteomics for Understanding Parkinson’s Disease Progression

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