Ultrasound-assisted extraction of natural antioxidants from betel leaves (Piper betle): Extraction kinetics and modeling

Ameena Ali; Xiao Yien Lim; Chien Hwa Chong; Siau Hui Mah; Bee Lin Chua

doi:10.1080/01496395.2018.1443137

Ultrasound-assisted extraction of natural antioxidants from betel leaves (Piper betle): Extraction kinetics and modeling

Ameena Ali^*, Xiao Yien Lim, Chien Hwa Chong, Siau Hui Mah, Bee Lin Chua

^*Corresponding author for this work

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Present study investigated the extraction kinetics of antioxidants from Piper betle by ultrasound-assisted extraction for three extraction variables: temperature, solute to solvent ratio and ethanol concentration. Based on the results of yield, total phenolic content and antioxidant activity, the optimum results were obtained at 50°C, 1:20 g/mL and 80% ethanol, respectively. Statistical coefficients of R² ≥ 0.961 and RMSE ≤ 0.508 for two-site kinetic model confirm the use of proposed models for simulation and prediction purpose. Comparison with ascorbic acid and butylated hydroxytoluene solidifies the use of Piper betle as feasible source of natural antioxidants. The presence of hydroxychavicol and eugenol was affirmed by high-performance liquid chromatography assay.

Original language	English
Pages (from-to)	2192-2205
Number of pages	14
Journal	Separation Science and Technology
Volume	53
Issue number	14
Early online date	8 Mar 2018
DOIs	https://doi.org/10.1080/01496395.2018.1443137
Publication status	Published - 22 Sept 2018

Keywords

antioxidant capacity
kinetic modeling
Piper betle
total phenolic content
ultrasound-assisted extraction

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering
Process Chemistry and Technology
Filtration and Separation

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Cite this

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abstract = "Present study investigated the extraction kinetics of antioxidants from Piper betle by ultrasound-assisted extraction for three extraction variables: temperature, solute to solvent ratio and ethanol concentration. Based on the results of yield, total phenolic content and antioxidant activity, the optimum results were obtained at 50°C, 1:20 g/mL and 80% ethanol, respectively. Statistical coefficients of R2 ≥ 0.961 and RMSE ≤ 0.508 for two-site kinetic model confirm the use of proposed models for simulation and prediction purpose. Comparison with ascorbic acid and butylated hydroxytoluene solidifies the use of Piper betle as feasible source of natural antioxidants. The presence of hydroxychavicol and eugenol was affirmed by high-performance liquid chromatography assay.",

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AU - Mah, Siau Hui

AU - Chua, Bee Lin

PY - 2018/9/22

Y1 - 2018/9/22

N2 - Present study investigated the extraction kinetics of antioxidants from Piper betle by ultrasound-assisted extraction for three extraction variables: temperature, solute to solvent ratio and ethanol concentration. Based on the results of yield, total phenolic content and antioxidant activity, the optimum results were obtained at 50°C, 1:20 g/mL and 80% ethanol, respectively. Statistical coefficients of R2 ≥ 0.961 and RMSE ≤ 0.508 for two-site kinetic model confirm the use of proposed models for simulation and prediction purpose. Comparison with ascorbic acid and butylated hydroxytoluene solidifies the use of Piper betle as feasible source of natural antioxidants. The presence of hydroxychavicol and eugenol was affirmed by high-performance liquid chromatography assay.

AB - Present study investigated the extraction kinetics of antioxidants from Piper betle by ultrasound-assisted extraction for three extraction variables: temperature, solute to solvent ratio and ethanol concentration. Based on the results of yield, total phenolic content and antioxidant activity, the optimum results were obtained at 50°C, 1:20 g/mL and 80% ethanol, respectively. Statistical coefficients of R2 ≥ 0.961 and RMSE ≤ 0.508 for two-site kinetic model confirm the use of proposed models for simulation and prediction purpose. Comparison with ascorbic acid and butylated hydroxytoluene solidifies the use of Piper betle as feasible source of natural antioxidants. The presence of hydroxychavicol and eugenol was affirmed by high-performance liquid chromatography assay.

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KW - kinetic modeling

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Ultrasound-assisted extraction of natural antioxidants from betel leaves (Piper betle): Extraction kinetics and modeling

Abstract

Keywords

ASJC Scopus subject areas

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