Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoaltermonas Luteoviolacea

Z. Jiang; K. G. Boyd; A. Mearns-Spragg; D. R. Adams; P. C. Wright; J. G. Burgess

doi:10.1080/10575630008043781

Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoaltermonas Luteoviolacea

Z. Jiang
, K. G. Boyd
, A. Mearns-Spragg
, D. R. Adams
, P. C. Wright
, J. G. Burgess

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.

Original language	English
Pages (from-to)	435-440
Number of pages	6
Journal	Natural Product Letters
Volume	14
Issue number	6
DOIs	https://doi.org/10.1080/10575630008043781
Publication status	Published - 2000

Keywords

2, 4-dibromo-6-chlorophenol
Antibiotic
Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline)
Cyclo-(L-prolyl-L-glycine)
Pseudoalteromonas luteoviolacea

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/10575630008043781

Cite this

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title = "Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoaltermonas Luteoviolacea",

abstract = "Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.",

keywords = "2, 4-dibromo-6-chlorophenol, Antibiotic, Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), Cyclo-(L-prolyl-L-glycine), Pseudoalteromonas luteoviolacea",

author = "Z. Jiang and Boyd, \{K. G.\} and A. Mearns-Spragg and Adams, \{D. R.\} and Wright, \{P. C.\} and Burgess, \{J. G.\}",

year = "2000",

doi = "10.1080/10575630008043781",

language = "English",

volume = "14",

pages = "435--440",

journal = "Natural Product Letters",

publisher = "Taylor \& Francis",

number = "6",

}

TY - JOUR

T1 - Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoaltermonas Luteoviolacea

AU - Jiang, Z.

AU - Boyd, K. G.

AU - Mearns-Spragg, A.

AU - Adams, D. R.

AU - Wright, P. C.

AU - Burgess, J. G.

PY - 2000

Y1 - 2000

N2 - Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.

AB - Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.

KW - 2, 4-dibromo-6-chlorophenol

KW - Antibiotic

KW - Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline)

KW - Cyclo-(L-prolyl-L-glycine)

KW - Pseudoalteromonas luteoviolacea

UR - https://www.scopus.com/pages/publications/0034487304

U2 - 10.1080/10575630008043781

DO - 10.1080/10575630008043781

M3 - Article

VL - 14

SP - 435

EP - 440

JO - Natural Product Letters

JF - Natural Product Letters

IS - 6

ER -

Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoaltermonas Luteoviolacea

Abstract

Keywords

UN SDGs

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