Translating Stochastic CLS into Maude

Thomas Anung Basuki*, Antonio Cerone, Paolo Milazzo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

This paper describes preliminary results on the application of statistical model-checking to systems described with Stochastic CLS. Stochastic CLS is a formalism based on term rewriting that allows biomolecular systems to be described by taking into account their structure and by allowing very general events to be modelled. Statistical model-checking is an analysis technique that permits properties of a system to be studied on the results of a number of stochastic simulations. We choose Real-Time Maude as a tool that supports the modelling and analysis of systems with real-time properties. We adapt Gillespie's algorithm for simulating chemical systems into our approach. The resulting method is applied to analyse some simple examples and a model of the lactose operon regulation in E.coli.

Original languageEnglish
Pages (from-to)37-58
Number of pages22
JournalElectronic Notes in Theoretical Computer Science
Volume227
DOIs
Publication statusPublished - 4 Jan 2009

Keywords

  • biological system
  • Calculus of Looping Sequences
  • Maude
  • model-checking

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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