Abstract
A ceph-3-emcarboxylic acid reacted with diphenylphosphoryl azide-toluene-t-butyl alcohol-triethylamine to give the 4a- and 4ß-t-butoxycarbonylceph-2-ems and a 4-t-butoxyformamidoceph-2-em. Interconversion studies on the 4a- and 4ß-esters were performed. Reaction in the presence of excess of sodium azide gave as the sole ß-lactam product a 4-t-butoxyformamidoceph-3-em.
Original language | English |
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Pages (from-to) | 1659-1660 |
Number of pages | 2 |
Journal | Journal of the Chemical Society, Perkin Transactions 1 |
Publication status | Published - 1979 |