Transformation of cephalosporins

Preparation of a 3-methyl-3-nitro-4- hydroxyiminocepham

Malcolm M Campbell, Stephen J Ray

Research output: Contribution to journalArticle

Abstract

The reaction of N2O3, with 3-methyl-7ß- phenoxyacetamidoceph-3-em-4-carboxylic acid gives, by an addition- decarboxylation sequence, 3a-methyl-3ß-nitro-4(E)-hydroxyimino- 7ß-phenoxyacetamidocepham-4-carboxylic acid.

Original languageEnglish
Pages (from-to)665-666
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number14
Publication statusPublished - 1980

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Cephalosporins
Carboxylic Acids
Decarboxylation

Cite this

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title = "Transformation of cephalosporins: Preparation of a 3-methyl-3-nitro-4- hydroxyiminocepham",
abstract = "The reaction of N2O3, with 3-methyl-7{\ss}- phenoxyacetamidoceph-3-em-4-carboxylic acid gives, by an addition- decarboxylation sequence, 3a-methyl-3{\ss}-nitro-4(E)-hydroxyimino- 7{\ss}-phenoxyacetamidocepham-4-carboxylic acid.",
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journal = "Journal of the Chemical Society, Chemical Communications",
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publisher = "Chemical Society",
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Transformation of cephalosporins : Preparation of a 3-methyl-3-nitro-4- hydroxyiminocepham. / Campbell, Malcolm M; Ray, Stephen J.

In: Journal of the Chemical Society, Chemical Communications, No. 14, 1980, p. 665-666.

Research output: Contribution to journalArticle

TY - JOUR

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T2 - Preparation of a 3-methyl-3-nitro-4- hydroxyiminocepham

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AU - Ray, Stephen J

PY - 1980

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AB - The reaction of N2O3, with 3-methyl-7ß- phenoxyacetamidoceph-3-em-4-carboxylic acid gives, by an addition- decarboxylation sequence, 3a-methyl-3ß-nitro-4(E)-hydroxyimino- 7ß-phenoxyacetamidocepham-4-carboxylic acid.

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JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

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