Towards rational de novo design of peptides for inorganic interfaces

M. J. Biggs; M. Mijajlovic

Towards rational de novo design of peptides for inorganic interfaces

M. J. Biggs
, M. Mijajlovic

University Executive

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Protein adsorption at inorganic surfaces is highly relevant to nano- and bionanotechnology. Just two examples of great significance are the use of specific peptide sequences to control cell deposition on tissue scaffolds, and the tethering of bio-photosynthetic reaction centers on electrodes to harvest light for power generation and hydrogen production. Understanding of the behavior of proteins in such situations and the design of surface-binding proteins for technological applications is currently limited by the largely empirical approaches used. We are, therefore, developing the application of molecular modeling to the elucidation of the behavior of peptides at fluid/solid interfaces - in this talk, we will provide details of these models and their application to the study of peptides at fluid/solid interfaces and their de novo rational design.

Original language	English
Title of host publication	Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation
Subtitle of host publication	Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show
Publisher	CRC Press
Pages	666-669
Number of pages	4
Volume	3
ISBN (Print)	9781420085051
Publication status	Published - 1 Jun 2008
Event	2008 NSTI Nanotechnology Conference and Trade Show - Boston, United States Duration: 1 Jun 2008 → 5 Jun 2008

Conference

Conference	2008 NSTI Nanotechnology Conference and Trade Show
Country/Territory	United States
City	Boston
Period	1/06/08 → 5/06/08

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 7 Affordable and Clean Energy

Keywords

Biosensors
Nanoelectronics
Nanophotonics
Surface binding peptides
Tissue engineering

ASJC Scopus subject areas

Mechanical Engineering

Cite this

@inproceedings{1150c72d181848eb97c6dbf209947d0e,

title = "Towards rational de novo design of peptides for inorganic interfaces",

abstract = "Protein adsorption at inorganic surfaces is highly relevant to nano- and bionanotechnology. Just two examples of great significance are the use of specific peptide sequences to control cell deposition on tissue scaffolds, and the tethering of bio-photosynthetic reaction centers on electrodes to harvest light for power generation and hydrogen production. Understanding of the behavior of proteins in such situations and the design of surface-binding proteins for technological applications is currently limited by the largely empirical approaches used. We are, therefore, developing the application of molecular modeling to the elucidation of the behavior of peptides at fluid/solid interfaces - in this talk, we will provide details of these models and their application to the study of peptides at fluid/solid interfaces and their de novo rational design.",

keywords = "Biosensors, Nanoelectronics, Nanophotonics, Surface binding peptides, Tissue engineering",

author = "Biggs, \{M. J.\} and M. Mijajlovic",

year = "2008",

month = jun,

day = "1",

language = "English",

isbn = "9781420085051",

volume = "3",

pages = "666--669",

booktitle = "Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation",

publisher = "CRC Press",

note = "2008 NSTI Nanotechnology Conference and Trade Show ; Conference date: 01-06-2008 Through 05-06-2008",

}

Biggs, MJ & Mijajlovic, M 2008, Towards rational de novo design of peptides for inorganic interfaces. in Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation: Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show. vol. 3, CRC Press, pp. 666-669, 2008 NSTI Nanotechnology Conference and Trade Show, Boston, Massachusetts, United States, 1/06/08.

Towards rational de novo design of peptides for inorganic interfaces. / Biggs, M. J.; Mijajlovic, M.
Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation: Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show. Vol. 3 CRC Press, 2008. p. 666-669.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Towards rational de novo design of peptides for inorganic interfaces

AU - Biggs, M. J.

AU - Mijajlovic, M.

PY - 2008/6/1

Y1 - 2008/6/1

N2 - Protein adsorption at inorganic surfaces is highly relevant to nano- and bionanotechnology. Just two examples of great significance are the use of specific peptide sequences to control cell deposition on tissue scaffolds, and the tethering of bio-photosynthetic reaction centers on electrodes to harvest light for power generation and hydrogen production. Understanding of the behavior of proteins in such situations and the design of surface-binding proteins for technological applications is currently limited by the largely empirical approaches used. We are, therefore, developing the application of molecular modeling to the elucidation of the behavior of peptides at fluid/solid interfaces - in this talk, we will provide details of these models and their application to the study of peptides at fluid/solid interfaces and their de novo rational design.

AB - Protein adsorption at inorganic surfaces is highly relevant to nano- and bionanotechnology. Just two examples of great significance are the use of specific peptide sequences to control cell deposition on tissue scaffolds, and the tethering of bio-photosynthetic reaction centers on electrodes to harvest light for power generation and hydrogen production. Understanding of the behavior of proteins in such situations and the design of surface-binding proteins for technological applications is currently limited by the largely empirical approaches used. We are, therefore, developing the application of molecular modeling to the elucidation of the behavior of peptides at fluid/solid interfaces - in this talk, we will provide details of these models and their application to the study of peptides at fluid/solid interfaces and their de novo rational design.

KW - Biosensors

KW - Nanoelectronics

KW - Nanophotonics

KW - Surface binding peptides

KW - Tissue engineering

UR - https://www.scopus.com/pages/publications/52649133325

M3 - Conference contribution

AN - SCOPUS:52649133325

SN - 9781420085051

VL - 3

SP - 666

EP - 669

BT - Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation

PB - CRC Press

T2 - 2008 NSTI Nanotechnology Conference and Trade Show

Y2 - 1 June 2008 through 5 June 2008

ER -

Towards rational de novo design of peptides for inorganic interfaces

Abstract

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

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