Time-related expression profiles for heat shock protein gene transcripts (HSP40, HSP70) in the central nervous system of Lymnaea stagnalis exposed to thermal stress

Nicola L. Foster, Ken Lukowiak, Theodore B. Henry

    Research output: Contribution to journalArticle

    15 Citations (Scopus)
    56 Downloads (Pure)

    Abstract

    Organisms exposed to environmental stressors respond by rapidly synthesising a suite of highly conserved proteins called heat shock proteins (HSPs). Environmental stress can also enhance and/or block memory formation, with longterm memory formation requiring gene activation and protein synthesis. Thermal stress in the pond snail Lymnaea stagnalis can enhance memory formation, and, in this study, the effect of thermal stress on HSP gene expression in the nervous system was investigated. Time-related expression profiles for HSP40 and HSP70 indicated rapid (<30 min) induction for both transcripts. For HSP40, induction was <20 fold relative to control and expression returned to control levels within 8 h, whereas HSP70 induction was >100 fold and expression did not return to control levels within 8 h.

    Original languageEnglish
    Article number e1040954
    Number of pages3
    JournalCommunicative and Integrative Biology
    Volume8
    Issue number3
    DOIs
    Publication statusPublished - 2015

    Keywords

    • Environmental stress
    • Gene expression
    • Learning
    • Long-term memory
    • Pond snail

    ASJC Scopus subject areas

    • Agricultural and Biological Sciences(all)

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