Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

Andrew L. Hook, Chien-Yi Chang, David J. Scurr, Robert Langer, Daniel G. Anderson, Paul Williams, Martyn C. Davies, Morgan R. Alexander*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)


    The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone rather, the surface composition of the polymer plays the key role.

    Original languageEnglish
    Pages (from-to)1020-1025
    Number of pages6
    JournalAdvanced Healthcare Materials
    Issue number7
    Publication statusPublished - Jul 2014


    • Escherichia coli
    • Switchable polymers
    • Thermal responsiveness
    • ToF-SIMS

    ASJC Scopus subject areas

    • Biomedical Engineering
    • Biomaterials
    • Pharmaceutical Science


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