Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

Andrew L. Hook; Chien-Yi Chang; David J. Scurr; Robert Langer; Daniel G. Anderson; Paul Williams; Martyn C. Davies; Morgan R. Alexander

doi:10.1002/adhm.201300518

Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

Andrew L. Hook, Chien-Yi Chang, David J. Scurr, Robert Langer, Daniel G. Anderson, Paul Williams, Martyn C. Davies, Morgan R. Alexander^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone rather, the surface composition of the polymer plays the key role.

Original language	English
Pages (from-to)	1020-1025
Number of pages	6
Journal	Advanced Healthcare Materials
Volume	3
Issue number	7
DOIs	https://doi.org/10.1002/adhm.201300518
Publication status	Published - Jul 2014

Keywords

Escherichia coli
Switchable polymers
Thermal responsiveness
ToF-SIMS

ASJC Scopus subject areas

Biomedical Engineering
Biomaterials
Pharmaceutical Science

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10.1002/adhm.201300518Licence: Creative Commons: Attribution (CC-BY)

Cite this

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abstract = "The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone rather, the surface composition of the polymer plays the key role.",

keywords = "Escherichia coli, Switchable polymers, Thermal responsiveness, ToF-SIMS",

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AU - Hook, Andrew L.

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AU - Langer, Robert

AU - Anderson, Daniel G.

AU - Williams, Paul

AU - Davies, Martyn C.

AU - Alexander, Morgan R.

PY - 2014/7

Y1 - 2014/7

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AB - The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone rather, the surface composition of the polymer plays the key role.

KW - Escherichia coli

KW - Switchable polymers

KW - Thermal responsiveness

KW - ToF-SIMS

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M3 - Article

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Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

Abstract

Keywords

ASJC Scopus subject areas

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