The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

A. S. Frame; R. H. Wightman; G. Mackenzie

The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

A. S. Frame, R. H. Wightman, G. Mackenzie

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

Original language	English
Pages (from-to)	363-366
Number of pages	4
Journal	Nucleosides and Nucleotides
Volume	14
Issue number	3-5
Publication status	Published - 1995

Cite this

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title = "The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines",

abstract = "5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.",

author = "Frame, \{A. S.\} and Wightman, \{R. H.\} and G. Mackenzie",

year = "1995",

language = "English",

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pages = "363--366",

journal = "Nucleosides and Nucleotides",

publisher = "Marcel Dekker Inc.",

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T1 - The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

AU - Frame, A. S.

AU - Wightman, R. H.

AU - Mackenzie, G.

PY - 1995

Y1 - 1995

N2 - 5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

AB - 5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

UR - https://www.scopus.com/pages/publications/0029060536

M3 - Article

VL - 14

SP - 363

EP - 366

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 3-5

ER -

The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

Abstract

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