The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

A. S. Frame; R. H. Wightman; G. Mackenzie

The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

A. S. Frame
, R. H. Wightman
, G. Mackenzie

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

Original language	English
Pages (from-to)	363-366
Number of pages	4
Journal	Nucleosides and Nucleotides
Volume	14
Issue number	3-5
Publication status	Published - 1995

Cite this

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title = "The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines",

abstract = "5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.",

author = "Frame, \{A. S.\} and Wightman, \{R. H.\} and G. Mackenzie",

year = "1995",

language = "English",

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pages = "363--366",

journal = "Nucleosides and Nucleotides",

publisher = "Marcel Dekker Inc.",

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T1 - The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

AU - Frame, A. S.

AU - Wightman, R. H.

AU - Mackenzie, G.

PY - 1995

Y1 - 1995

N2 - 5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

AB - 5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

UR - https://www.scopus.com/pages/publications/0029060536

M3 - Article

VL - 14

SP - 363

EP - 366

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 3-5

ER -

The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

Abstract

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