The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines

A. S. Frame, R. H. Wightman, G. Mackenzie

Research output: Contribution to journalArticle

Abstract

5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.

Original languageEnglish
Pages (from-to)363-366
Number of pages4
JournalNucleosides and Nucleotides
Volume14
Issue number3-5
Publication statusPublished - 1995

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