The STA2 and MEL1 genes of Saccharomyces cerevisiae are idiomorphic

C. A. Lyness, C. R. Jones, P. G. Meaden

    Research output: Contribution to journalArticle

    Abstract

    The STA2 (glucoamylase) gene of Saccharomyces cerevisiae has been mapped close to the end of the left arm of chromosome II. Meiotic analysis of a cross between a haploid strain containing STA2, and another strain carrying the melibiase gene MEL1 (which is known to be at the end of the left arm of chromosome II) produced parental ditype tetrads only. Since there is no significant DNA sequence similarity between the STA2 and MEL1 genes, or their respective flanking regions, we conclude that these two genes are carried by separate non-hybridizing sequences of chromosomal DNA, either of which can reside at the end of the left arm of chromosome II. By analogy with the mating-type locus of Neurospora crassa, we suggest that the STA2 and MEL1 genes are idiomorphs with respect to one another.

    Original languageEnglish
    Pages (from-to)92-94
    Number of pages3
    JournalCurrent Genetics
    Volume23
    Issue number1
    DOIs
    Publication statusPublished - 1993

    Keywords

    • Gene mapping
    • Idiomorphism
    • Saccharomyces cerevisiae

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