The STA2 and MEL1 genes of Saccharomyces cerevisiae are idiomorphic

C. A. Lyness; C. R. Jones; P. G. Meaden

doi:10.1007/BF00336753

The STA2 and MEL1 genes of Saccharomyces cerevisiae are idiomorphic

C. A. Lyness, C. R. Jones, P. G. Meaden

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Abstract

The STA2 (glucoamylase) gene of Saccharomyces cerevisiae has been mapped close to the end of the left arm of chromosome II. Meiotic analysis of a cross between a haploid strain containing STA2, and another strain carrying the melibiase gene MEL1 (which is known to be at the end of the left arm of chromosome II) produced parental ditype tetrads only. Since there is no significant DNA sequence similarity between the STA2 and MEL1 genes, or their respective flanking regions, we conclude that these two genes are carried by separate non-hybridizing sequences of chromosomal DNA, either of which can reside at the end of the left arm of chromosome II. By analogy with the mating-type locus of Neurospora crassa, we suggest that the STA2 and MEL1 genes are idiomorphs with respect to one another.

Original language	English
Pages (from-to)	92-94
Number of pages	3
Journal	Current Genetics
Volume	23
Issue number	1
DOIs	https://doi.org/10.1007/BF00336753
Publication status	Published - 1993

Keywords

Gene mapping
Idiomorphism
Saccharomyces cerevisiae

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10.1007/BF00336753

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title = "The STA2 and MEL1 genes of Saccharomyces cerevisiae are idiomorphic",

abstract = "The STA2 (glucoamylase) gene of Saccharomyces cerevisiae has been mapped close to the end of the left arm of chromosome II. Meiotic analysis of a cross between a haploid strain containing STA2, and another strain carrying the melibiase gene MEL1 (which is known to be at the end of the left arm of chromosome II) produced parental ditype tetrads only. Since there is no significant DNA sequence similarity between the STA2 and MEL1 genes, or their respective flanking regions, we conclude that these two genes are carried by separate non-hybridizing sequences of chromosomal DNA, either of which can reside at the end of the left arm of chromosome II. By analogy with the mating-type locus of Neurospora crassa, we suggest that the STA2 and MEL1 genes are idiomorphs with respect to one another.",

keywords = "Gene mapping, Idiomorphism, Saccharomyces cerevisiae",

author = "Lyness, {C. A.} and Jones, {C. R.} and Meaden, {P. G.}",

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T1 - The STA2 and MEL1 genes of Saccharomyces cerevisiae are idiomorphic

AU - Lyness, C. A.

AU - Jones, C. R.

AU - Meaden, P. G.

PY - 1993

Y1 - 1993

N2 - The STA2 (glucoamylase) gene of Saccharomyces cerevisiae has been mapped close to the end of the left arm of chromosome II. Meiotic analysis of a cross between a haploid strain containing STA2, and another strain carrying the melibiase gene MEL1 (which is known to be at the end of the left arm of chromosome II) produced parental ditype tetrads only. Since there is no significant DNA sequence similarity between the STA2 and MEL1 genes, or their respective flanking regions, we conclude that these two genes are carried by separate non-hybridizing sequences of chromosomal DNA, either of which can reside at the end of the left arm of chromosome II. By analogy with the mating-type locus of Neurospora crassa, we suggest that the STA2 and MEL1 genes are idiomorphs with respect to one another.

AB - The STA2 (glucoamylase) gene of Saccharomyces cerevisiae has been mapped close to the end of the left arm of chromosome II. Meiotic analysis of a cross between a haploid strain containing STA2, and another strain carrying the melibiase gene MEL1 (which is known to be at the end of the left arm of chromosome II) produced parental ditype tetrads only. Since there is no significant DNA sequence similarity between the STA2 and MEL1 genes, or their respective flanking regions, we conclude that these two genes are carried by separate non-hybridizing sequences of chromosomal DNA, either of which can reside at the end of the left arm of chromosome II. By analogy with the mating-type locus of Neurospora crassa, we suggest that the STA2 and MEL1 genes are idiomorphs with respect to one another.

KW - Gene mapping

KW - Idiomorphism

KW - Saccharomyces cerevisiae

U2 - 10.1007/BF00336753

DO - 10.1007/BF00336753

M3 - Article

SN - 0172-8083

VL - 23

SP - 92

EP - 94

JO - Current Genetics

JF - Current Genetics

IS - 1

ER -

The STA2 and MEL1 genes of Saccharomyces cerevisiae are idiomorphic

Abstract

Keywords

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