The role of the available sulphydryl group in liver butyryl-coenzyme a synthetase

Callum J. Campbell, Milton V. Park

    Research output: Contribution to journalArticle

    Abstract

    1. 1. Butyryl-CoA synthetase from acetone-dried ox liver mitochondria can be activated up to 80% by low concentrations of iodoacetate with the concomitant modification of one available enzyme thiol group. 2. 2. The relative molecular mass of the carboxymethylated enzyme was unchanged, and there were no major changes in the complex kinetic properties of the enzyme. 3. 3. Extraction experiments on liver mitochondria indicate that in vivo the enzyme is linked to a mitochondrial membrane by a bond cleavable by disulphide bond reducing agents. © 1987.

    Original languageEnglish
    Pages (from-to)539-544
    Number of pages6
    JournalInternational Journal of Biochemistry
    Volume19
    Issue number6
    Publication statusPublished - 1987

    Fingerprint Dive into the research topics of 'The role of the available sulphydryl group in liver butyryl-coenzyme a synthetase'. Together they form a unique fingerprint.

    Cite this