The effects of dopamine agonists and antagonists on Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes

A H Sawas; John C Gilbert

doi:10.1016/0006-2952(82)90377-X

The effects of dopamine agonists and antagonists on Na⁺, K⁺-ATPase and Mg²⁺-ATPase activities of synaptosomes

A H Sawas, John C Gilbert

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The effects of dopamine agonists and antagonists on the Na⁺, K⁺-ATPase and Mg²⁺-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.

Original language	English
Pages (from-to)	1531-1533
Number of pages	3
Journal	Biochemical Pharmacology
Volume	31
Issue number	8
DOIs	https://doi.org/10.1016/0006-2952(82)90377-X
Publication status	Published - 1982

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@article{a91fc7d8b25040ed82ada3c4da631d2a,

title = "The effects of dopamine agonists and antagonists on Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes",

abstract = "The effects of dopamine agonists and antagonists on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.",

author = "Sawas, {A H} and Gilbert, {John C}",

year = "1982",

doi = "10.1016/0006-2952(82)90377-X",

language = "English",

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T1 - The effects of dopamine agonists and antagonists on Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes

AU - Sawas, A H

AU - Gilbert, John C

PY - 1982

Y1 - 1982

N2 - The effects of dopamine agonists and antagonists on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.

AB - The effects of dopamine agonists and antagonists on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.

U2 - 10.1016/0006-2952(82)90377-X

DO - 10.1016/0006-2952(82)90377-X

M3 - Article

VL - 31

SP - 1531

EP - 1533

JO - Biochemical Pharmacology

JF - Biochemical Pharmacology

IS - 8

ER -

The effects of dopamine agonists and antagonists on Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes

Abstract

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The effects of dopamine agonists and antagonists on Na⁺, K⁺-ATPase and Mg²⁺-ATPase activities of synaptosomes