The effects of dopamine agonists and antagonists on Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes

A H Sawas, John C Gilbert

Research output: Contribution to journalArticle

Abstract

The effects of dopamine agonists and antagonists on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.

Original languageEnglish
Pages (from-to)1531-1533
Number of pages3
JournalBiochemical Pharmacology
Volume31
Issue number8
DOIs
Publication statusPublished - 1982

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Ca(2+) Mg(2+)-ATPase
Dopamine Antagonists
Synaptosomes
Dopamine Agonists
1-(2-pyrimidyl)-4-(3,4-dihydroxybenzyl)piperazine
Dopamine
Piribedil
Apomorphine
Enzymes
Cerebral Cortex
sodium-translocating ATPase
ADTN
catechol

Cite this

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abstract = "The effects of dopamine agonists and antagonists on the Na+, K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.",
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The effects of dopamine agonists and antagonists on Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes. / Sawas, A H; Gilbert, John C.

In: Biochemical Pharmacology, Vol. 31, No. 8, 1982, p. 1531-1533.

Research output: Contribution to journalArticle

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