The bioprinting roadmap

Wei Sun*, Binil Starly, Andrew C. Daly, Jason A. Burdick, Jürgen Groll, Gregor Skeldon, Wenmiao Shu, Yasuyuki Sakai, Marie Shinohara, Masaki Nishikawa, Jinah Jang, Dong Woo Cho, Minghao Nie, Shoji Takeuchi, Serge Ostrovidov, Ali Khademhosseini, Roger D. Kamm, Vladimir Mironov, Lorenzo Moroni, Ibrahim T. Ozbolat

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

326 Citations (Scopus)
116 Downloads (Pure)

Abstract

This bioprinting roadmap features salient advances in selected applications of the technique and highlights the status of current developments and challenges, as well as envisioned advances in science and technology, to address the challenges to the young and evolving technique. The topics covered in this roadmap encompass the broad spectrum of bioprinting; from cell expansion and novel bioink development to cell/stem cell printing, from organoid-based tissue organization to bioprinting of human-scale tissue structures, and from building cell/tissue/organ-on-a-chip to biomanufacturing of multicellular engineered living systems. The emerging application of printing-in-space and an overview of bioprinting technologies are also included in this roadmap. Due to the rapid pace of methodological advancements in bioprinting techniques and wide-ranging applications, the direction in which the field should advance is not immediately clear. This bioprinting roadmap addresses this unmet need by providing a comprehensive summary and recommendations useful to experienced researchers and newcomers to the field.

Original languageEnglish
Article number022002
JournalBiofabrication
Volume12
Issue number2
Early online date7 Feb 2020
DOIs
Publication statusPublished - Apr 2020

Keywords

  • biofabrication
  • bioprinting
  • cell printing
  • disease models
  • in vitro biological models
  • organ-on-a-chip
  • organoids

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Biomaterials
  • Biomedical Engineering

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