Targeted epidermal delivery of vaccines from coated micro-nanoprojection patches

Tarl W. Prow, Xianfeng Chen, Michael Crichton, Yash Tiwari, Francesca Gradassi, Kristin Raphelli, Donna Mahony, Germain Fernando, Michael S. Roberts, Mark A. F. Kendall

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Transcutaneous vaccine delivery has the potential to greatly improve immunization effectiveness and safety. This work characterizes our novel micro-nanoneedles and their payload release profile in vitro and in vivo. We found that these dry-coated micro-nanoneedles quickly deliver the payload to the epidermis.

Original languageEnglish
Title of host publicationProceedings of the 2008 International Conference on Nanoscience and Nanotechnology, ICONN 2008
Place of PublicationPiscataway, New Jersey
Pages125-128
Number of pages4
DOIs
Publication statusPublished - 2008
Event2008 International Conference on Nanoscience and Nanotechnology - Melbourne, VIC, Australia
Duration: 25 Feb 200829 Feb 2008

Conference

Conference2008 International Conference on Nanoscience and Nanotechnology
Abbreviated titleICONN 2008
CountryAustralia
CityMelbourne, VIC
Period25/02/0829/02/08

Keywords

  • Drug delivery
  • Microneedle
  • Nano-microprojection
  • Releas, skin
  • Transcutaneous
  • Vaccine

ASJC Scopus subject areas

  • Biotechnology
  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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  • Cite this

    Prow, T. W., Chen, X., Crichton, M., Tiwari, Y., Gradassi, F., Raphelli, K., Mahony, D., Fernando, G., Roberts, M. S., & Kendall, M. A. F. (2008). Targeted epidermal delivery of vaccines from coated micro-nanoprojection patches. In Proceedings of the 2008 International Conference on Nanoscience and Nanotechnology, ICONN 2008 (pp. 125-128). [4639262]. https://doi.org/10.1109/ICONN.2008.4639262