Synthesis of some hydroxamic acids related to uridine: Potential inhibitors of ribonucleoside diphosphate reductase

Peter Currid, Richard H. Wightman

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

5-(N-Hydroxy)carboxamidouridine (5) and 5-(N-hydroxy)carboxamido- methyluridine (6) have been synthesized; these hydroxamic acids incorporate a radical trap into a nucleoside structure, and are designed as potential inhibitors of ribonucleotide diphosphate reductase.

Original languageEnglish
Pages (from-to)115-128
Number of pages14
JournalNucleosides and Nucleotides
Volume16
Issue number1-2
Publication statusPublished - 1997

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