Synthesis of 2,3-benzo-fused 1-oxacephems

Malcolm M Campbell, Kenneth H Nelson, A. Forbes Cameron

Research output: Contribution to journalArticle

Abstract

4-Acetoxyazetidin-2-one (2) reacted with salicylaldehyde and 2-hydroxyphenyl ketones to give tricyclic hydroxy-amine products, and the reaction with ethyl 2-hydroxyphenylacetate was employed in the synthesis of a 2,3-benzo-fused ethoxycarbonyl 1-oxa analogue of the cephems.

Original languageEnglish
Pages (from-to)532-533
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number12
DOIs
Publication statusPublished - 1979

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Ketones
Amines
salicylaldehyde

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Campbell, Malcolm M ; Nelson, Kenneth H ; Cameron, A. Forbes. / Synthesis of 2,3-benzo-fused 1-oxacephems. In: Journal of the Chemical Society, Chemical Communications. 1979 ; No. 12. pp. 532-533.
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Synthesis of 2,3-benzo-fused 1-oxacephems. / Campbell, Malcolm M; Nelson, Kenneth H; Cameron, A. Forbes.

In: Journal of the Chemical Society, Chemical Communications, No. 12, 1979, p. 532-533.

Research output: Contribution to journalArticle

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AU - Campbell, Malcolm M

AU - Nelson, Kenneth H

AU - Cameron, A. Forbes

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AB - 4-Acetoxyazetidin-2-one (2) reacted with salicylaldehyde and 2-hydroxyphenyl ketones to give tricyclic hydroxy-amine products, and the reaction with ethyl 2-hydroxyphenylacetate was employed in the synthesis of a 2,3-benzo-fused ethoxycarbonyl 1-oxa analogue of the cephems.

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JF - Journal of the Chemical Society, Chemical Communications

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