Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

Tracy D Nixon; Scott J Dalgarno; Caroline V Ward; Mingliang Jiang; Malcolm A Halcrow; Colin A Kilner; Mark Thornton-Pett; Terence P Kee

doi:10.1016/j.crci.2003.10.020

Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

Tracy D Nixon
, Scott J Dalgarno
, Caroline V Ward
, Mingliang Jiang
, Malcolm A Halcrow
, Colin A Kilner
, Mark Thornton-Pett
, Terence P Kee

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of

Original language	English
Pages (from-to)	809-821
Number of pages	13
Journal	Comptes Rendus Chimie
Volume	7
Issue number	8-9
DOIs	https://doi.org/10.1016/j.crci.2003.10.020
Publication status	Published - Aug 2004

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10.1016/j.crci.2003.10.020

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title = "Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action",

abstract = "The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of ",

author = "Nixon, \{Tracy D\} and Dalgarno, \{Scott J\} and Ward, \{Caroline V\} and Mingliang Jiang and Halcrow, \{Malcolm A\} and Kilner, \{Colin A\} and Mark Thornton-Pett and Kee, \{Terence P\}",

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T1 - Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

AU - Nixon, Tracy D

AU - Dalgarno, Scott J

AU - Ward, Caroline V

AU - Jiang, Mingliang

AU - Halcrow, Malcolm A

AU - Kilner, Colin A

AU - Thornton-Pett, Mark

AU - Kee, Terence P

PY - 2004/8

Y1 - 2004/8

N2 - The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of

AB - The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of

U2 - 10.1016/j.crci.2003.10.020

DO - 10.1016/j.crci.2003.10.020

M3 - Article

SN - 1631-0748

VL - 7

SP - 809

EP - 821

JO - Comptes Rendus Chimie

JF - Comptes Rendus Chimie

IS - 8-9

ER -

Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

Abstract

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