Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

Tracy D Nixon; Scott J Dalgarno; Caroline V Ward; Mingliang Jiang; Malcolm A Halcrow; Colin A Kilner; Mark Thornton-Pett; Terence P Kee

doi:10.1016/j.crci.2003.10.020

Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

Tracy D Nixon, Scott J Dalgarno, Caroline V Ward, Mingliang Jiang, Malcolm A Halcrow, Colin A Kilner, Mark Thornton-Pett, Terence P Kee

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of

Original language	English
Pages (from-to)	809-821
Number of pages	13
Journal	Comptes Rendus Chimie
Volume	7
Issue number	8-9
DOIs	https://doi.org/10.1016/j.crci.2003.10.020
Publication status	Published - Aug 2004

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10.1016/j.crci.2003.10.020

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title = "Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action",

abstract = "The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of ",

author = "Nixon, {Tracy D} and Dalgarno, {Scott J} and Ward, {Caroline V} and Mingliang Jiang and Halcrow, {Malcolm A} and Kilner, {Colin A} and Mark Thornton-Pett and Kee, {Terence P}",

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AU - Nixon, Tracy D

AU - Dalgarno, Scott J

AU - Ward, Caroline V

AU - Jiang, Mingliang

AU - Halcrow, Malcolm A

AU - Kilner, Colin A

AU - Thornton-Pett, Mark

AU - Kee, Terence P

PY - 2004/8

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N2 - The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of

AB - The enantioselective addition of diorgano-H-phosphonates to aldehydes, the phospho-aldol reaction, is catalysed by both (R,R)-salcyen and (R,R)-salcyan complexes of aluminium at room temperature under aerobic conditions. However, whilst the former ligand system favours one absolute configuration of product alpha-hydroxyphosphonate ester, to the extent of

U2 - 10.1016/j.crci.2003.10.020

DO - 10.1016/j.crci.2003.10.020

M3 - Article

SN - 1631-0748

VL - 7

SP - 809

EP - 821

JO - Comptes Rendus Chimie

JF - Comptes Rendus Chimie

IS - 8-9

ER -

Stereocontrol in asymmetric phospho-aldol catalysis. Chirality relaying in action

Abstract

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