Statistical mapping of the effect of knee extension on thigh muscle viscoelastic properties using magnetic resonance elastography

Eric Barnhill, Paul Kennedy, Steven Hammer, Edwin J R van Beek, Colin Brown, Neil Roberts

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Skeletal muscle viscoelastic properties reflect muscle microstructure and neuromuscular activation. Elastographic methods, including magnetic resonance elastography, have been used to characterize muscle viscoelastic properties in terms of region of interest (ROI) measurements. The present study extended this approach to create thresholded pixel-by-pixel maps of viscoelastic properties of skeletal muscle during rest and knee extension in eleven subjects. ROI measurements were taken for individual quadricep muscles and the quadriceps region as a whole, and the viscoelastic parameter map pixels were statistically tested at positive false discovery rate q

Original languageEnglish
Pages (from-to)1675-1698
Number of pages24
JournalPhysiological Measurement
Volume34
Issue number12
DOIs
Publication statusPublished - Dec 2013

Keywords

  • elastography
  • magnetic Resonance Elastography
  • Skeletal Muscle
  • MULTIFREQUENCY MR ELASTOGRAPHY
  • HUMAN SKELETAL-MUSCLE
  • IN-VIVO
  • LIVER VISCOELASTICITY
  • LEAST-SQUARES
  • BRAIN
  • HEALTHY
  • TISSUE
  • VARIABILITY
  • STIFFNESS

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