Abstract
In this paper we study pattern formation arising in a system of a single reaction-diffusion equation coupled with subsystem of ordinary differential equations, describing spatially-distributed growth of clonal populations of precancerous cells, whose proliferation is controlled by growth factors diffusing in the extracellular medium and binding to the cell surface. We extend the results on the existence of nonhomogenous stationary solutions obtained in [9] to a general Hill-type production function and full parameter set. Using spectral analysis and perturbation theory we derive conditions for the linearized stability of such spatial patterns.
Original language | English |
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Pages (from-to) | 229-241 |
Number of pages | 13 |
Journal | Communications on Pure and Applied Analysis |
Volume | 11 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2012 |
Keywords
- Linearized stability
- Pattern formation
- Reaction-diffusion equations
- Spectral analysis
ASJC Scopus subject areas
- Analysis
- Applied Mathematics