Sodium functionalized graphene oxide coated titanium plates for improved corrosion resistance and cell viability

Mohana Marimuthu, Murugan Veerapandian, Subramaniyan Ramasundaram, Seok Won Hong, P. Sudhagar*, Srinivasan Nagarajan, V. Raman, Eisuke Ito, Sanghyo Kim, Kyusik Yun, Yong Soo Kang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


Surface functionalization is an important process that has been adopted to well explore the applications of nanomaterials. In this context, we demonstrate the sodium functionalized graphene oxide (NaGO) as an excellent candidate for increasing the life time of titanium (Ti) based ortho-implants. As-prepared aqueous dispersion of NaGO was used to assemble NaGO sheets on commercially pure Ti (CpTi) plates by heat controlled spin coating. The resulting wrinkled NaGO sheets play a dual role in implant material, i.e., passive layer against corrosion and biocompatible scaffold for cell viability. The preparation, physicochemical properties, and biocompatibility of NaGO coatings formed on CpTi were reported. The electrochemical polarization studies demonstrate the relative susceptibility of control GO and NaGO coatings to corrosion, which outline that the NaGO coating act as a geometric blocking layer and hence prevent the implant surface from contacting corrosive media. The immunofluorescence and cell proliferation studies performed using human dermal fibroblasts cells showed that NaGO coatings significantly (P < 0.05) enhanced the cellular viability for longer in vitro culture period (15 days) than control GO and pristine CpTi.

Original languageEnglish
Pages (from-to)124-131
Number of pages8
JournalApplied Surface Science
Publication statusPublished - 28 Feb 2014


  • Biocompatibility
  • Corrosion
  • Graphene oxide
  • Orthopedic implants
  • Sodium
  • Titanium

ASJC Scopus subject areas

  • General Chemistry
  • Condensed Matter Physics
  • General Physics and Astronomy
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films


Dive into the research topics of 'Sodium functionalized graphene oxide coated titanium plates for improved corrosion resistance and cell viability'. Together they form a unique fingerprint.

Cite this