TY - JOUR
T1 - Sodium Bicarbonate and Time-to-Exhaustion Cycling Performance
T2 - A Retrospective Analysis Exploring the Mediating Role of Expectation
AU - Gurton, William H.
AU - Matta, Guilherme G.
AU - Gough, Lewis Anthony
AU - Ranchordas, Mayur Krachna
AU - King, David G.
AU - Hurst, Philip
N1 - Funding Information:
We gratefully acknowledge the commitment of all participants.
Publisher Copyright:
© 2023, The Author(s).
PY - 2023/7/31
Y1 - 2023/7/31
N2 - Background: Research has shown that ingesting 0.3 g·kg−1 body mass sodium bicarbonate (NaHCO3) can improve time-to-exhaustion (TTE) cycling performance, but the influence of psychophysiological mechanisms on ergogenic effects is not yet understood. Objective: This study retrospectively examined whether changes in TTE cycling performance are mediated by positive expectations of receiving NaHCO3 and/or the decline in blood bicarbonate during exercise. Methods: In a randomised, crossover, counterbalanced, double-blind, placebo-controlled design, 12 recreationally trained cyclists (maximal oxygen consumption, 54.4 ± 5.7 mL·kg·min−1) performed four TTE cycling tests 90 min after consuming: (1) 0.3 g·kg−1 body mass NaHCO3 in 5 mL·kg−1 body mass solution, (2) 0.03 g·kg−1 body mass sodium chloride in solution (placebo), (3) 0.3 g·kg−1 body mass NaHCO3 in capsules and (4) cornflour in capsules (placebo). Prior to exercise, participants rated on 1–5 Likert type scales how much they expected the treatment they believe had been given would improve performance. Capillary blood samples were measured for acid-base balance at baseline, pre-exercise and post-exercise. Results: Administering NaHCO3 in solution and capsules improved TTE compared with their respective placebos (solution: 27.0 ± 21.9 s, p = 0.001; capsules: 23.0 ± 28.1 s, p = 0.016). Compared to capsules, NaHCO3 administered via solution resulted in a higher expectancy about the benefits on TTE cycling performance (Median: 3.5 vs. 2.5, Z = 2.135, p = 0.033). Decline in blood bicarbonate during exercise was higher for NaHCO3 given in solution compared to capsules (2.7 ± 2.1 mmol·L−1, p = 0.001). Mediation analyses showed that improvements in TTE cycling were indirectly related to expectancy and decline in blood bicarbonate when NaHCO3 was administered in solution but not capsules. Conclusions: Participants’ higher expectations when NaHCO3 is administered in solution could result in them exerting themselves harder during TTE cycling, which subsequently leads to a greater decline in blood bicarbonate and larger improvements in performance. Key Points: Ingesting 0.3
AB - Background: Research has shown that ingesting 0.3 g·kg−1 body mass sodium bicarbonate (NaHCO3) can improve time-to-exhaustion (TTE) cycling performance, but the influence of psychophysiological mechanisms on ergogenic effects is not yet understood. Objective: This study retrospectively examined whether changes in TTE cycling performance are mediated by positive expectations of receiving NaHCO3 and/or the decline in blood bicarbonate during exercise. Methods: In a randomised, crossover, counterbalanced, double-blind, placebo-controlled design, 12 recreationally trained cyclists (maximal oxygen consumption, 54.4 ± 5.7 mL·kg·min−1) performed four TTE cycling tests 90 min after consuming: (1) 0.3 g·kg−1 body mass NaHCO3 in 5 mL·kg−1 body mass solution, (2) 0.03 g·kg−1 body mass sodium chloride in solution (placebo), (3) 0.3 g·kg−1 body mass NaHCO3 in capsules and (4) cornflour in capsules (placebo). Prior to exercise, participants rated on 1–5 Likert type scales how much they expected the treatment they believe had been given would improve performance. Capillary blood samples were measured for acid-base balance at baseline, pre-exercise and post-exercise. Results: Administering NaHCO3 in solution and capsules improved TTE compared with their respective placebos (solution: 27.0 ± 21.9 s, p = 0.001; capsules: 23.0 ± 28.1 s, p = 0.016). Compared to capsules, NaHCO3 administered via solution resulted in a higher expectancy about the benefits on TTE cycling performance (Median: 3.5 vs. 2.5, Z = 2.135, p = 0.033). Decline in blood bicarbonate during exercise was higher for NaHCO3 given in solution compared to capsules (2.7 ± 2.1 mmol·L−1, p = 0.001). Mediation analyses showed that improvements in TTE cycling were indirectly related to expectancy and decline in blood bicarbonate when NaHCO3 was administered in solution but not capsules. Conclusions: Participants’ higher expectations when NaHCO3 is administered in solution could result in them exerting themselves harder during TTE cycling, which subsequently leads to a greater decline in blood bicarbonate and larger improvements in performance. Key Points: Ingesting 0.3
KW - Beliefs
KW - Ergogenic aids
KW - Extracellular buffering
KW - High-intensity exercise
KW - Placebo effect
UR - http://www.scopus.com/inward/record.url?scp=85166247677&partnerID=8YFLogxK
U2 - 10.1186/s40798-023-00612-5
DO - 10.1186/s40798-023-00612-5
M3 - Article
C2 - 37523028
AN - SCOPUS:85166247677
SN - 2199-1170
VL - 9
JO - Sports Medicine - Open
JF - Sports Medicine - Open
IS - 1
M1 - 65
ER -
