Single line particle focusing using a vibrating bubble

Hoang Van Phan; Muhsincan Sesen; T. Alan; A. Neild

doi:10.1063/1.4901951

Single line particle focusing using a vibrating bubble

Hoang Van Phan, Muhsincan Sesen, T. Alan, A. Neild

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17 Citations (Scopus)

Abstract

In this study, we present a method for fine focusing of microparticles using a vibrating air bubble. Fluorescent polystyrene particles of 2.01 and 6.60 μm are shown to be focused along the edge of a 50-μm-wide channel. The mechanism is determined to be shear stresses caused by the boundary layer on the vibrating gas/liquid meniscus. Experiments show that the focussing region width reduces with higher excitation amplitude, focusing is not as sensitive towards the flow rate as the excitation frequency, and there is an optimal bubble radius. Finally, we show that red blood cells and 6.60 μm particles can be focused into what is effectively a single line.

Original language	English
Number of pages	5
Journal	Applied Physics Letters
Volume	105
Issue number	19
DOIs	https://doi.org/10.1063/1.4901951
Publication status	Published - 2014

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title = "Single line particle focusing using a vibrating bubble",

abstract = "In this study, we present a method for fine focusing of microparticles using a vibrating air bubble. Fluorescent polystyrene particles of 2.01 and 6.60 μm are shown to be focused along the edge of a 50-μm-wide channel. The mechanism is determined to be shear stresses caused by the boundary layer on the vibrating gas/liquid meniscus. Experiments show that the focussing region width reduces with higher excitation amplitude, focusing is not as sensitive towards the flow rate as the excitation frequency, and there is an optimal bubble radius. Finally, we show that red blood cells and 6.60 μm particles can be focused into what is effectively a single line.",

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AU - Phan, Hoang Van

AU - Sesen, Muhsincan

AU - Alan, T.

AU - Neild, A.

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PY - 2014

Y1 - 2014

N2 - In this study, we present a method for fine focusing of microparticles using a vibrating air bubble. Fluorescent polystyrene particles of 2.01 and 6.60 μm are shown to be focused along the edge of a 50-μm-wide channel. The mechanism is determined to be shear stresses caused by the boundary layer on the vibrating gas/liquid meniscus. Experiments show that the focussing region width reduces with higher excitation amplitude, focusing is not as sensitive towards the flow rate as the excitation frequency, and there is an optimal bubble radius. Finally, we show that red blood cells and 6.60 μm particles can be focused into what is effectively a single line.

AB - In this study, we present a method for fine focusing of microparticles using a vibrating air bubble. Fluorescent polystyrene particles of 2.01 and 6.60 μm are shown to be focused along the edge of a 50-μm-wide channel. The mechanism is determined to be shear stresses caused by the boundary layer on the vibrating gas/liquid meniscus. Experiments show that the focussing region width reduces with higher excitation amplitude, focusing is not as sensitive towards the flow rate as the excitation frequency, and there is an optimal bubble radius. Finally, we show that red blood cells and 6.60 μm particles can be focused into what is effectively a single line.

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VL - 105

JO - Applied Physics Letters

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ER -

Single line particle focusing using a vibrating bubble

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