This paper describes two simple high-performance liquid chromatographic (HPLC) methods for the quantitation of nafimidone and its major metabolite in plasma. The methods employ UV and fluorescence detection, the latter involving wavelength switching to optimise sensitivity. The methods have been used to analyse plasma obtained following the administration of nafimidone hydrochloride to dog and monkey.
|Number of pages||6|
|Journal||Journal of Chromatography - Biomedical Applications|
|Publication status||Published - 1983|