Simulation of superresolution holography for optical tweezers

Laura C. Thomson, Yannick Boissel, Graeme Whyte, Eric Yao, Johannes Courtial

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Optical tweezers manipulate microscopic particles using foci of light beams. Their performance is therefore limited by diffraction. Using computer simulations of a model system, we investigate the application of superresolution holography for two-dimensional (2D) light shaping in optical tweezers, which can beat the diffraction limit. We use the direct-search and Gerchberg algorithms to shape the center of a light beam into one or two bright spots; we do not constrain the remainder of the beam. We demonstrate that superresolution algorithms can significantly improve the normalized stiffness of an optical trap and the minimum separation at which neighboring traps can be resolved. We also test if such algorithms can be used interactively, as is desirable in optical tweezers.
Original languageEnglish
Article number023015
JournalNew Journal of Physics
Publication statusPublished - 13 Feb 2008


Dive into the research topics of 'Simulation of superresolution holography for optical tweezers'. Together they form a unique fingerprint.

Cite this