Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations

Marcos Veguillas, Georgina Margaret Rosair, Magnus William Paul Bebbington, Ai-Lan Lee

Research output: Contribution to journalArticle

Abstract

We report a silver-induced switching of regioselectivity in gold-catalyzed reactions, and we provide mechanistic evidence to suggest a true “silver effect”: that is, one that is implicated in the catalytic process itself, via σ-gold π-silver acetylides. These results are of significance because they clearly show that the use of silver as halide abstractors in gold-catalyzed reactions may result in “silver effects” when terminal alkyne substrates are involved.
Original languageEnglish
Pages (from-to)2552-2557
Number of pages6
JournalACS Catalysis
Volume9
Issue number3
Early online date14 Feb 2019
DOIs
Publication statusPublished - 1 Mar 2019

Fingerprint

Silver
Gold
Regioselectivity
Alkynes
Substrates

Keywords

  • digold
  • gold
  • gold acetylide
  • hydroamination
  • regiodivergent
  • silver
  • silver-effect

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Veguillas, Marcos ; Rosair, Georgina Margaret ; Bebbington, Magnus William Paul ; Lee, Ai-Lan. / Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations. In: ACS Catalysis. 2019 ; Vol. 9, No. 3. pp. 2552-2557.
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Veguillas, M, Rosair, GM, Bebbington, MWP & Lee, A-L 2019, 'Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations', ACS Catalysis, vol. 9, no. 3, pp. 2552-2557. https://doi.org/10.1021/acscatal.9b00249

Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations. / Veguillas, Marcos; Rosair, Georgina Margaret; Bebbington, Magnus William Paul; Lee, Ai-Lan.

In: ACS Catalysis, Vol. 9, No. 3, 01.03.2019, p. 2552-2557.

Research output: Contribution to journalArticle

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