Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Stuart W. Naylor; Allen Flockhart; Pablo Nart; David George Emslie Smith; John F. Huntley; David L. Gally; J. Christopher Low

doi:10.1128/AEM.02670-06

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Stuart W. Naylor, Allen Flockhart, Pablo Nart, David George Emslie Smith, John F. Huntley, David L. Gally, J. Christopher Low

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

Original language	English
Pages (from-to)	3765-3767
Number of pages	3
Journal	Applied and Environmental Microbiology
Volume	73
Issue number	11
DOIs	https://doi.org/10.1128/AEM.02670-06
Publication status	Published - Jun 2007

Keywords

Animals
Antibodies, Bacterial
Cattle
Cattle Diseases
Enzyme-Linked Immunosorbent Assay
Escherichia coli Infections
Escherichia coli O157
Feces
Immunoglobulin A
Immunoglobulin G

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10.1128/AEM.02670-06

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title = "Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain",

abstract = "Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.",

keywords = "Animals, Antibodies, Bacterial, Cattle, Cattle Diseases, Enzyme-Linked Immunosorbent Assay, Escherichia coli Infections, Escherichia coli O157, Feces, Immunoglobulin A, Immunoglobulin G",

author = "Naylor, {Stuart W.} and Allen Flockhart and Pablo Nart and Smith, {David George Emslie} and Huntley, {John F.} and Gally, {David L.} and Low, {J. Christopher}",

year = "2007",

month = jun,

doi = "10.1128/AEM.02670-06",

language = "English",

volume = "73",

pages = "3765--3767",

journal = "Applied and Environmental Microbiology",

issn = "0099-2240",

publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

AU - Naylor, Stuart W.

AU - Flockhart, Allen

AU - Nart, Pablo

AU - Smith, David George Emslie

AU - Huntley, John F.

AU - Gally, David L.

AU - Low, J. Christopher

PY - 2007/6

Y1 - 2007/6

N2 - Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

AB - Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

KW - Animals

KW - Antibodies, Bacterial

KW - Cattle

KW - Cattle Diseases

KW - Enzyme-Linked Immunosorbent Assay

KW - Escherichia coli Infections

KW - Escherichia coli O157

KW - Feces

KW - Immunoglobulin A

KW - Immunoglobulin G

U2 - 10.1128/AEM.02670-06

DO - 10.1128/AEM.02670-06

M3 - Article

C2 - 17449700

SN - 0099-2240

VL - 73

SP - 3765

EP - 3767

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 11

ER -

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Abstract

Keywords

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