Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Stuart W. Naylor, Allen Flockhart, Pablo Nart, David George Emslie Smith, John F. Huntley, David L. Gally, J. Christopher Low

Research output: Contribution to journalArticle

Abstract

Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

Original languageEnglish
Pages (from-to)3765-3767
Number of pages3
JournalApplied and Environmental Microbiology
Volume73
Issue number11
DOIs
Publication statusPublished - Jun 2007

Keywords

  • Animals
  • Antibodies, Bacterial
  • Cattle
  • Cattle Diseases
  • Enzyme-Linked Immunosorbent Assay
  • Escherichia coli Infections
  • Escherichia coli O157
  • Feces
  • Immunoglobulin A
  • Immunoglobulin G

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