TY - JOUR
T1 - Revolutionizing Prokaryotic Systematics Through Next-Generation Sequencing
AU - Sangal, Vartul
AU - Nieminen, Leena
AU - Tucker, Nicholas P.
AU - Hoskisson, Paul A.
PY - 2014
Y1 - 2014
N2 - Next-generation sequencing has revolutionized modern research in all life sciences. It has been applied in studying evolution, global transmission and local adaptation of pathogens, microbial ecology, genetics and physiology. In this chapter, we have provided a brief summary of recent advances in sequencing technologies and easy to use bioinformatic tools to analyse sequence data, with a focus on prokaryotic biology. We have emphasized the importance of routinely applying whole genome sequencing in prokaryotic systematics, evolution, genotyping and functional characterization.
AB - Next-generation sequencing has revolutionized modern research in all life sciences. It has been applied in studying evolution, global transmission and local adaptation of pathogens, microbial ecology, genetics and physiology. In this chapter, we have provided a brief summary of recent advances in sequencing technologies and easy to use bioinformatic tools to analyse sequence data, with a focus on prokaryotic biology. We have emphasized the importance of routinely applying whole genome sequencing in prokaryotic systematics, evolution, genotyping and functional characterization.
UR - https://www.scopus.com/pages/publications/84919419857
U2 - 10.1016/bs.mim.2014.07.001
DO - 10.1016/bs.mim.2014.07.001
M3 - Review article
SN - 0580-9517
VL - 41
SP - 75
EP - 101
JO - Methods in Microbiology
JF - Methods in Microbiology
ER -