Repeated measurement of the gas exchange threshold: Relative size of measurement and biological variabilities

Alasdair G. Thin; Gabrielle E. Kelly; Leslie Daly; Paul McLoughlin

doi:10.1016/j.compbiomed.2004.06.004

Repeated measurement of the gas exchange threshold: Relative size of measurement and biological variabilities

Alasdair G. Thin, Gabrielle E. Kelly, Leslie Daly, Paul McLoughlin

Research output: Contribution to journal › Article › peer-review

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Abstract

If an individual's gas exchange threshold (GET) is measured on several separate occasions, without a change in aerobic fitness, a random variability will be observed. However, it is not known how much of this variability is biologically determined and how much results from variability in the calibration and measurement processes. The statistical re-sampling technique of Bootstrapping was used to estimate the variability of the GET on a single occasion. This analysis provides the first estimate of the combined contribution of breath-by-breath measurement and calibration processes (6%), to the total between-occasion random variability, leaving biological variability to account for the remainder of the imprecision in the measurement of the GET. © 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	703-716
Number of pages	14
Journal	Computers in Biology and Medicine
Volume	35
Issue number	8
DOIs	https://doi.org/10.1016/j.compbiomed.2004.06.004
Publication status	Published - Oct 2005

Keywords

Aerobic fitness
Bootstrapping
Breath-by-breath
Exercise test
Gas exchange threshold
Limits of repeatability
Method variability
Reliability
Reproducibility

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10.1016/j.compbiomed.2004.06.004

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title = "Repeated measurement of the gas exchange threshold: Relative size of measurement and biological variabilities",

abstract = "If an individual's gas exchange threshold (GET) is measured on several separate occasions, without a change in aerobic fitness, a random variability will be observed. However, it is not known how much of this variability is biologically determined and how much results from variability in the calibration and measurement processes. The statistical re-sampling technique of Bootstrapping was used to estimate the variability of the GET on a single occasion. This analysis provides the first estimate of the combined contribution of breath-by-breath measurement and calibration processes (6%), to the total between-occasion random variability, leaving biological variability to account for the remainder of the imprecision in the measurement of the GET. {\textcopyright} 2004 Elsevier Ltd. All rights reserved.",

keywords = "Aerobic fitness, Bootstrapping, Breath-by-breath, Exercise test, Gas exchange threshold, Limits of repeatability, Method variability, Reliability, Reproducibility",

author = "Thin, {Alasdair G.} and Kelly, {Gabrielle E.} and Leslie Daly and Paul McLoughlin",

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TY - JOUR

T1 - Repeated measurement of the gas exchange threshold

T2 - Relative size of measurement and biological variabilities

AU - Thin, Alasdair G.

AU - Kelly, Gabrielle E.

AU - Daly, Leslie

AU - McLoughlin, Paul

PY - 2005/10

Y1 - 2005/10

N2 - If an individual's gas exchange threshold (GET) is measured on several separate occasions, without a change in aerobic fitness, a random variability will be observed. However, it is not known how much of this variability is biologically determined and how much results from variability in the calibration and measurement processes. The statistical re-sampling technique of Bootstrapping was used to estimate the variability of the GET on a single occasion. This analysis provides the first estimate of the combined contribution of breath-by-breath measurement and calibration processes (6%), to the total between-occasion random variability, leaving biological variability to account for the remainder of the imprecision in the measurement of the GET. © 2004 Elsevier Ltd. All rights reserved.

AB - If an individual's gas exchange threshold (GET) is measured on several separate occasions, without a change in aerobic fitness, a random variability will be observed. However, it is not known how much of this variability is biologically determined and how much results from variability in the calibration and measurement processes. The statistical re-sampling technique of Bootstrapping was used to estimate the variability of the GET on a single occasion. This analysis provides the first estimate of the combined contribution of breath-by-breath measurement and calibration processes (6%), to the total between-occasion random variability, leaving biological variability to account for the remainder of the imprecision in the measurement of the GET. © 2004 Elsevier Ltd. All rights reserved.

KW - Aerobic fitness

KW - Bootstrapping

KW - Breath-by-breath

KW - Exercise test

KW - Gas exchange threshold

KW - Limits of repeatability

KW - Method variability

KW - Reliability

KW - Reproducibility

U2 - 10.1016/j.compbiomed.2004.06.004

DO - 10.1016/j.compbiomed.2004.06.004

M3 - Article

SN - 0010-4825

VL - 35

SP - 703

EP - 716

JO - Computers in Biology and Medicine

JF - Computers in Biology and Medicine

IS - 8

ER -

Repeated measurement of the gas exchange threshold: Relative size of measurement and biological variabilities

Abstract

Keywords

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