Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices

Gergely Simon; Jose Marques-Hueso; Marc P. Y. Desmulliez; Anne L. Bernassau; Dany Roolvink; G. Burns; P. A. G. Cormack; Marco A. B. Andrade; Julien Reboud; Jonathan M. Cooper; Mathis O. Riehle

Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices

Gergely Simon
, Jose Marques-Hueso
, Marc P. Y. Desmulliez
, Anne L. Bernassau
, Dany Roolvink
, G. Burns
, P. A. G. Cormack
, Marco A. B. Andrade
, Julien Reboud
, Jonathan M. Cooper
, Mathis O. Riehle

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

136 Downloads (Pure)

Abstract

Advances in diagnostics, cell and stem cell technologies drive the development of applicationspecific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for label-free, high recovery, cell and particle separation and isolation in tissue engineering and targeted drug delivery. In this paper, we present two methods of separating particles in a microfluidic channel. The first method uses custom-made micro-particles and by changing the acoustic contrast factor, the micro-particles shift from acoustic node to antinodes, compared to commercialised micro-particles. The second method relies on shifting the acoustic standing wave in a pattern called dynamic acoustic field. We demonstrate that both methods separate particles up to 100%.

Original language	English
Title of host publication	Proceedings of the 24th International Congress on Sound and Vibration
Publisher	International Institute of Acoustics and Vibrations
Pages	1-7
Number of pages	7
ISBN (Print)	9781906913274
Publication status	Published - 2017
Event	24th International Congress on Sound and Vibration: London Calling - Park Plaza Westminster Bridge Hotel, London, United Kingdom Duration: 23 Jul 2017 → 27 Jul 2017 Conference number: 24 http://www.icsv24.org/

Publication series

Name	Proceedings of the International Congress on Sound and Vibration
Publisher	International Institute of Acoustics and Vibration
ISSN (Print)	2329-3675

Conference

Conference	24th International Congress on Sound and Vibration
Abbreviated title	ICSV24
Country/Territory	United Kingdom
City	London
Period	23/07/17 → 27/07/17
Internet address	http://www.icsv24.org/

Keywords

Acoustic radiation force
Cell sorting

ASJC Scopus subject areas

Acoustics and Ultrasonics

Access to Document

Download pdfAccepted author manuscript, 930 KBLicence: Unspecified

https://www.iiav.org/archives_icsv_last/2017_icsv24/content/papers/papers/full_paper_218_20170604195147369.pdfLicence: Unspecified

Cite this

Simon, G., Marques-Hueso, J., Desmulliez, M. P. Y., Bernassau, A. L., Roolvink, D., Burns, G., Cormack, P. A. G., Andrade, M. A. B., Reboud, J., Cooper, J. M., & Riehle, M. O. (2017). Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices. In Proceedings of the 24th International Congress on Sound and Vibration (pp. 1-7). (Proceedings of the International Congress on Sound and Vibration). International Institute of Acoustics and Vibrations. https://www.iiav.org/archives_icsv_last/2017_icsv24/content/papers/papers/full_paper_218_20170604195147369.pdf

@inproceedings{a68bd299716c4a9fb86d37e7998a712c,

title = "Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices",

abstract = "Advances in diagnostics, cell and stem cell technologies drive the development of applicationspecific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for label-free, high recovery, cell and particle separation and isolation in tissue engineering and targeted drug delivery. In this paper, we present two methods of separating particles in a microfluidic channel. The first method uses custom-made micro-particles and by changing the acoustic contrast factor, the micro-particles shift from acoustic node to antinodes, compared to commercialised micro-particles. The second method relies on shifting the acoustic standing wave in a pattern called dynamic acoustic field. We demonstrate that both methods separate particles up to 100\%.",

keywords = "Acoustic radiation force, Cell sorting",

author = "Gergely Simon and Jose Marques-Hueso and Desmulliez, \{Marc P. Y.\} and Bernassau, \{Anne L.\} and Dany Roolvink and G. Burns and Cormack, \{P. A. G.\} and Andrade, \{Marco A. B.\} and Julien Reboud and Cooper, \{Jonathan M.\} and Riehle, \{Mathis O.\}",

year = "2017",

language = "English",

isbn = "9781906913274",

series = "Proceedings of the International Congress on Sound and Vibration",

publisher = "International Institute of Acoustics and Vibrations",

pages = "1--7",

booktitle = "Proceedings of the 24th International Congress on Sound and Vibration",

note = "24th International Congress on Sound and Vibration : London Calling, ICSV24 ; Conference date: 23-07-2017 Through 27-07-2017",

url = "http://www.icsv24.org/",

}

Simon, G, Marques-Hueso, J, Desmulliez, MPY , Bernassau, AL, Roolvink, D, Burns, G, Cormack, PAG, Andrade, MAB, Reboud, J, Cooper, JM & Riehle, MO 2017, Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices. in Proceedings of the 24th International Congress on Sound and Vibration. Proceedings of the International Congress on Sound and Vibration, International Institute of Acoustics and Vibrations, pp. 1-7, 24th International Congress on Sound and Vibration, London, United Kingdom, 23/07/17. <https://www.iiav.org/archives_icsv_last/2017_icsv24/content/papers/papers/full_paper_218_20170604195147369.pdf>

Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices. / Simon, Gergely; Marques-Hueso, Jose; Desmulliez, Marc P. Y. et al.
Proceedings of the 24th International Congress on Sound and Vibration. International Institute of Acoustics and Vibrations, 2017. p. 1-7 (Proceedings of the International Congress on Sound and Vibration).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices

AU - Simon, Gergely

AU - Marques-Hueso, Jose

AU - Desmulliez, Marc P. Y.

AU - Bernassau, Anne L.

AU - Roolvink, Dany

AU - Burns, G.

AU - Cormack, P. A. G.

AU - Andrade, Marco A. B.

AU - Reboud, Julien

AU - Cooper, Jonathan M.

AU - Riehle, Mathis O.

N1 - Conference code: 24

PY - 2017

Y1 - 2017

N2 - Advances in diagnostics, cell and stem cell technologies drive the development of applicationspecific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for label-free, high recovery, cell and particle separation and isolation in tissue engineering and targeted drug delivery. In this paper, we present two methods of separating particles in a microfluidic channel. The first method uses custom-made micro-particles and by changing the acoustic contrast factor, the micro-particles shift from acoustic node to antinodes, compared to commercialised micro-particles. The second method relies on shifting the acoustic standing wave in a pattern called dynamic acoustic field. We demonstrate that both methods separate particles up to 100%.

AB - Advances in diagnostics, cell and stem cell technologies drive the development of applicationspecific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for label-free, high recovery, cell and particle separation and isolation in tissue engineering and targeted drug delivery. In this paper, we present two methods of separating particles in a microfluidic channel. The first method uses custom-made micro-particles and by changing the acoustic contrast factor, the micro-particles shift from acoustic node to antinodes, compared to commercialised micro-particles. The second method relies on shifting the acoustic standing wave in a pattern called dynamic acoustic field. We demonstrate that both methods separate particles up to 100%.

KW - Acoustic radiation force

KW - Cell sorting

UR - https://www.scopus.com/pages/publications/85029429829

M3 - Conference contribution

AN - SCOPUS:85029429829

SN - 9781906913274

T3 - Proceedings of the International Congress on Sound and Vibration

SP - 1

EP - 7

BT - Proceedings of the 24th International Congress on Sound and Vibration

PB - International Institute of Acoustics and Vibrations

T2 - 24th International Congress on Sound and Vibration

Y2 - 23 July 2017 through 27 July 2017

ER -

Simon G, Marques-Hueso J, Desmulliez MPY , Bernassau AL, Roolvink D, Burns G et al. Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices. In Proceedings of the 24th International Congress on Sound and Vibration. International Institute of Acoustics and Vibrations. 2017. p. 1-7. (Proceedings of the International Congress on Sound and Vibration).

Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this