Reconfigurable particle separation by dynamic acoustic fields in microfluidic devices

Gergely Simon, Jose Marques-Hueso, Marc P. Y. Desmulliez, Anne L. Bernassau, Dany Roolvink, G. Burns, P. A. G. Cormack, Marco A. B. Andrade, Julien Reboud, Jonathan M. Cooper, Mathis O. Riehle

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
52 Downloads (Pure)

Abstract

Advances in diagnostics, cell and stem cell technologies drive the development of applicationspecific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for label-free, high recovery, cell and particle separation and isolation in tissue engineering and targeted drug delivery. In this paper, we present two methods of separating particles in a microfluidic channel. The first method uses custom-made micro-particles and by changing the acoustic contrast factor, the micro-particles shift from acoustic node to antinodes, compared to commercialised micro-particles. The second method relies on shifting the acoustic standing wave in a pattern called dynamic acoustic field. We demonstrate that both methods separate particles up to 100%.

Original languageEnglish
Title of host publicationProceedings of the 24th International Congress on Sound and Vibration
PublisherInternational Institute of Acoustics and Vibrations
Pages1-7
Number of pages7
ISBN (Print)9781906913274
Publication statusPublished - 2017
Event24th International Congress on Sound and Vibration: London Calling - Park Plaza Westminster Bridge Hotel, London, United Kingdom
Duration: 23 Jul 201727 Jul 2017
Conference number: 24
http://www.icsv24.org/

Publication series

NameProceedings of the International Congress on Sound and Vibration
PublisherInternational Institute of Acoustics and Vibration
ISSN (Print)2329-3675

Conference

Conference24th International Congress on Sound and Vibration
Abbreviated titleICSV24
CountryUnited Kingdom
CityLondon
Period23/07/1727/07/17
Internet address

Keywords

  • Acoustic radiation force
  • Cell sorting

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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