Crystallization of four di-O-alkyl-tris-p-carboxylatocalixarenes from a series of pyridine derivatives has been carried out to investigate the effect of introducing alkyl groups around the pyridine guest/template. Where single crystals were obtained, for 12 of 24 possible structures, in all but one case the calixarenes assemble with the pyridine derivative into hydrogen-bonded head-to-head dimers within extended bilayer or nanotubular arrays.
Kennedy, S., Dodgson, I. E., Beavers, C. M., Teat, S. J., & Dalgarno, S. J. (2012). Pyridine Directed Assembly of Di-O-Alkyl-tris-p-Carboxylatocalixarenes. Crystal Growth and Design, 12(2), 688-697. https://doi.org/10.1021/cg200887d