Production of 4-hydroxyfuranones in simple media by fermentation

Yasuo Hayashida, Hiroshi Kuriyama, Kenryo Nishimura, J. Colin Slaughter

    Research output: Contribution to journalArticle

    Abstract

    Both 2,5-dimethyl-3(2H)-furanone (DMHF) and 2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (EMHF) were produced at concentrations up to 4 mg l-1 and 20 mg l-1 respectively by yeast fermentation of a heated mixture of a single amino acid and a single sugar added to a yeast extract/peptone/glucose (YPG) medium. About 1 mg DMHF l-1 was also produced from precursors in the autoclaved YPG medium but EMHF formation depended entirely on the presence of a heated ribose/amino acid mixture. Glutamate was the best precursor amino acid for both furanones. Formation of EMHF showed a positive, non-linear response to ribose/glutamate concentration from 20 to 200 mM in the heated mixture.

    Original languageEnglish
    Pages (from-to)505-509
    Number of pages5
    JournalBiotechnology Letters
    Volume21
    Issue number6
    DOIs
    Publication statusPublished - 1999

    Fingerprint

    Yeast
    Fermentation
    Peptones
    Ribose
    Amino Acids
    Glutamic Acid
    Glucose
    Sugars

    Keywords

    • Hydroxyfuranones
    • Maillard reaction
    • Yeast
    • Zygosaccharomyces

    Cite this

    Hayashida, Y., Kuriyama, H., Nishimura, K., & Slaughter, J. C. (1999). Production of 4-hydroxyfuranones in simple media by fermentation. Biotechnology Letters, 21(6), 505-509. https://doi.org/10.1023/A:1005548322173
    Hayashida, Yasuo ; Kuriyama, Hiroshi ; Nishimura, Kenryo ; Slaughter, J. Colin. / Production of 4-hydroxyfuranones in simple media by fermentation. In: Biotechnology Letters. 1999 ; Vol. 21, No. 6. pp. 505-509.
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    Hayashida, Y, Kuriyama, H, Nishimura, K & Slaughter, JC 1999, 'Production of 4-hydroxyfuranones in simple media by fermentation', Biotechnology Letters, vol. 21, no. 6, pp. 505-509. https://doi.org/10.1023/A:1005548322173

    Production of 4-hydroxyfuranones in simple media by fermentation. / Hayashida, Yasuo; Kuriyama, Hiroshi; Nishimura, Kenryo; Slaughter, J. Colin.

    In: Biotechnology Letters, Vol. 21, No. 6, 1999, p. 505-509.

    Research output: Contribution to journalArticle

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