Production of 4-hydroxyfuranones in simple media by fermentation

Yasuo Hayashida; Hiroshi Kuriyama; Kenryo Nishimura; J. Colin Slaughter

doi:10.1023/A:1005548322173

Production of 4-hydroxyfuranones in simple media by fermentation

Yasuo Hayashida, Hiroshi Kuriyama, Kenryo Nishimura, J. Colin Slaughter

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Both 2,5-dimethyl-3(2H)-furanone (DMHF) and 2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (EMHF) were produced at concentrations up to 4 mg l^-1 and 20 mg l^-1 respectively by yeast fermentation of a heated mixture of a single amino acid and a single sugar added to a yeast extract/peptone/glucose (YPG) medium. About 1 mg DMHF l^-1 was also produced from precursors in the autoclaved YPG medium but EMHF formation depended entirely on the presence of a heated ribose/amino acid mixture. Glutamate was the best precursor amino acid for both furanones. Formation of EMHF showed a positive, non-linear response to ribose/glutamate concentration from 20 to 200 mM in the heated mixture.

Original language	English
Pages (from-to)	505-509
Number of pages	5
Journal	Biotechnology Letters
Volume	21
Issue number	6
DOIs	https://doi.org/10.1023/A:1005548322173
Publication status	Published - 1999

Keywords

Hydroxyfuranones
Maillard reaction
Yeast
Zygosaccharomyces

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abstract = "Both 2,5-dimethyl-3(2H)-furanone (DMHF) and 2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (EMHF) were produced at concentrations up to 4 mg l-1 and 20 mg l-1 respectively by yeast fermentation of a heated mixture of a single amino acid and a single sugar added to a yeast extract/peptone/glucose (YPG) medium. About 1 mg DMHF l-1 was also produced from precursors in the autoclaved YPG medium but EMHF formation depended entirely on the presence of a heated ribose/amino acid mixture. Glutamate was the best precursor amino acid for both furanones. Formation of EMHF showed a positive, non-linear response to ribose/glutamate concentration from 20 to 200 mM in the heated mixture.",

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T1 - Production of 4-hydroxyfuranones in simple media by fermentation

AU - Hayashida, Yasuo

AU - Kuriyama, Hiroshi

AU - Nishimura, Kenryo

AU - Slaughter, J. Colin

PY - 1999

Y1 - 1999

N2 - Both 2,5-dimethyl-3(2H)-furanone (DMHF) and 2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (EMHF) were produced at concentrations up to 4 mg l-1 and 20 mg l-1 respectively by yeast fermentation of a heated mixture of a single amino acid and a single sugar added to a yeast extract/peptone/glucose (YPG) medium. About 1 mg DMHF l-1 was also produced from precursors in the autoclaved YPG medium but EMHF formation depended entirely on the presence of a heated ribose/amino acid mixture. Glutamate was the best precursor amino acid for both furanones. Formation of EMHF showed a positive, non-linear response to ribose/glutamate concentration from 20 to 200 mM in the heated mixture.

AB - Both 2,5-dimethyl-3(2H)-furanone (DMHF) and 2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (EMHF) were produced at concentrations up to 4 mg l-1 and 20 mg l-1 respectively by yeast fermentation of a heated mixture of a single amino acid and a single sugar added to a yeast extract/peptone/glucose (YPG) medium. About 1 mg DMHF l-1 was also produced from precursors in the autoclaved YPG medium but EMHF formation depended entirely on the presence of a heated ribose/amino acid mixture. Glutamate was the best precursor amino acid for both furanones. Formation of EMHF showed a positive, non-linear response to ribose/glutamate concentration from 20 to 200 mM in the heated mixture.

KW - Hydroxyfuranones

KW - Maillard reaction

KW - Yeast

KW - Zygosaccharomyces

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DO - 10.1023/A:1005548322173

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JO - Biotechnology Letters

JF - Biotechnology Letters

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Production of 4-hydroxyfuranones in simple media by fermentation

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Keywords

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