Predator vs aliens: bacteria interactions with Acanthamoeba

Naveed Ahmed Khan*, Ruqaiyyah Siddiqui

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


By interactions with other microbes, free-living amoebae play a significant role in microbiology, environmental biology, physiology, cellular interactions, ecology and evolution. Here, we discuss astonishing interactions of bacteria and amoebae, in the light of evolution and functional aspects impacting human health. In favourable environmental conditions, the interaction of Acanthamoeba with non-virulent bacteria results in lysis of the bacteria. However, the interaction with weak-virulent bacteria results in a symbiotic relationship or amoebal lysis may occur. The microbial survival of amoebae in harsh environments, ability to interact with bacteria, and their ability to aid transmission to susceptible hosts is of great concern to human, animal and ecosystem health.
Original languageEnglish
Pages (from-to)869-874
Number of pages6
Issue number7
Publication statusPublished - Jun 2014


  • protist
  • prokaryotes
  • microbial interactions


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