Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model

M. Yong; F. Melchels; C. Vaquette; D. Hutmacher; C. Adam; M. Domingos; P. Bartolo

Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model

M. Yong^*, F. Melchels, C. Vaquette, D. Hutmacher, C. Adam, M. Domingos, P. Bartolo

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recom-binant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.

Original language	English
Title of host publication	Innovative Developments in Virtual and Physical Prototyping
Subtitle of host publication	Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011
Publisher	CRC Press
Pages	89-92
Number of pages	4
ISBN (Print)	9780415684187
Publication status	Published - 2012
Event	5th International Conference on Advanced Research in Virtual and Physical Prototyping - Leiria, Portugal Duration: 28 Sept 2011 → 1 Oct 2011

Conference

Conference	5th International Conference on Advanced Research in Virtual and Physical Prototyping
Abbreviated title	VR@P 2011
Country/Territory	Portugal
City	Leiria
Period	28/09/11 → 1/10/11

ASJC Scopus subject areas

Artificial Intelligence
Computer Science Applications
Software

Cite this

Yong, M., Melchels, F., Vaquette, C., Hutmacher, D., Adam, C., Domingos, M., & Bartolo, P. (2012). Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model. In Innovative Developments in Virtual and Physical Prototyping: Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011 (pp. 89-92). CRC Press.

Yong, M. ; Melchels, F. ; Vaquette, C. et al. / Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model. Innovative Developments in Virtual and Physical Prototyping: Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011. CRC Press, 2012. pp. 89-92

@inproceedings{57bee8d06f6f449d90c4df52e1213da6,

title = "Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model",

abstract = "We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recom-binant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.",

author = "M. Yong and F. Melchels and C. Vaquette and D. Hutmacher and C. Adam and M. Domingos and P. Bartolo",

year = "2012",

language = "English",

isbn = "9780415684187",

pages = "89--92",

booktitle = "Innovative Developments in Virtual and Physical Prototyping",

publisher = "CRC Press",

note = "5th International Conference on Advanced Research in Virtual and Physical Prototyping, VR@P 2011 ; Conference date: 28-09-2011 Through 01-10-2011",

}

Yong, M, Melchels, F, Vaquette, C, Hutmacher, D, Adam, C, Domingos, M & Bartolo, P 2012, Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model. in Innovative Developments in Virtual and Physical Prototyping: Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011. CRC Press, pp. 89-92, 5th International Conference on Advanced Research in Virtual and Physical Prototyping, Leiria, Portugal, 28/09/11.

Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model. / Yong, M.; Melchels, F.; Vaquette, C. et al.
Innovative Developments in Virtual and Physical Prototyping: Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011. CRC Press, 2012. p. 89-92.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model

AU - Yong, M.

AU - Melchels, F.

AU - Vaquette, C.

AU - Hutmacher, D.

AU - Adam, C.

AU - Domingos, M.

AU - Bartolo, P.

PY - 2012

Y1 - 2012

N2 - We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recom-binant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.

AB - We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recom-binant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.

UR - https://www.scopus.com/pages/publications/84856745376

M3 - Conference contribution

AN - SCOPUS:84856745376

SN - 9780415684187

SP - 89

EP - 92

BT - Innovative Developments in Virtual and Physical Prototyping

PB - CRC Press

T2 - 5th International Conference on Advanced Research in Virtual and Physical Prototyping

Y2 - 28 September 2011 through 1 October 2011

ER -

Yong M, Melchels F, Vaquette C, Hutmacher D, Adam C, Domingos M et al. Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model. In Innovative Developments in Virtual and Physical Prototyping: Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011. CRC Press. 2012. p. 89-92

Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model

Abstract

Conference

ASJC Scopus subject areas

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