Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion model

M. Yong*, F. Melchels, C. Vaquette, D. Hutmacher, C. Adam, M. Domingos, P. Bartolo

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recom-binant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.

Original languageEnglish
Title of host publicationInnovative Developments in Virtual and Physical Prototyping
Subtitle of host publicationProceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September - 1 October, 2011
PublisherCRC Press
Pages89-92
Number of pages4
ISBN (Print)9780415684187
Publication statusPublished - 2012
Event5th International Conference on Advanced Research in Virtual and Physical Prototyping - Leiria, Portugal
Duration: 28 Sept 20111 Oct 2011

Conference

Conference5th International Conference on Advanced Research in Virtual and Physical Prototyping
Abbreviated titleVR@P 2011
Country/TerritoryPortugal
CityLeiria
Period28/09/111/10/11

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Science Applications
  • Software

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