Triethanolamine is a widely used model electron donor that enables a fast screening of the photocatalyst parameters in both, homogeneous and heterogeneous scenarios. We report a new role of triethanolamine in heterogeneous photoregeneration of cofactor molecules – nicotinamide adenine dinucleotide (NADH) – using state-of-the-art heterogeneous photocatalysts. In contrast to the common model involving the light-induced electrons and holes generation to reduce the substrate and oxidize triethanolamine simultaneously, we identified glycolaldehyde as a stable product of triethanolamine degradation capable of reducing NAD+. Triethanolamine, apart from playing a role of a precursor for reducing agent, maintains the alkalinity of the solution to drive the reduction. Our findings offer a fresh insight into the triethanolamine-assisted photocatalysis because glycolaldehyde as such have generally been neglected in mechanistic considerations. Moreover, a spatial and temporal decoupling of the photocatalyst from the substrate reduction reaction minimizes the product re-oxidation, thus implying a relevant feature for the real-world applications using a continuous flow setting.
- Microporous conjugated polymer
- NADH photoregeneration
ASJC Scopus subject areas
- Environmental Science(all)
- Process Chemistry and Technology
Kinastowska, K., Liu, J., Tobin, J. M., Rakovich, Y., Vilela, F., Xu, Z., Bartkowiak, W., & Grzelczak, M. (2019). Photocatalytic cofactor regeneration involving triethanolamine revisited: the critical role of glycolaldehyde. Applied Catalysis B: Environmental, 243, 686-692. https://doi.org/10.1016/j.apcatb.2018.10.077