Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds

F. P. Melchels; D. W. Grijpma; J. Feijen

doi:10.1016/j.jconrel.2006.09.070

Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds

F. P. Melchels^*, D. W. Grijpma, J. Feijen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

38 Downloads (Pure)

Abstract

In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.

Original language	English
Pages (from-to)	e98-e100
Number of pages	3
Journal	Journal of Controlled Release
Volume	116
Issue number	2
DOIs	https://doi.org/10.1016/j.jconrel.2006.09.070
Publication status	Published - 28 Nov 2006

ASJC Scopus subject areas

Pharmaceutical Science

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abstract = "In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.",

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AU - Melchels, F. P.

AU - Grijpma, D. W.

AU - Feijen, J.

PY - 2006/11/28

Y1 - 2006/11/28

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AB - In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.

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ER -

Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds

Abstract

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