TY - JOUR
T1 - Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds
AU - Melchels, F. P.
AU - Grijpma, D. W.
AU - Feijen, J.
PY - 2006/11/28
Y1 - 2006/11/28
N2 - In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.
AB - In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.
UR - http://www.scopus.com/inward/record.url?scp=34548730854&partnerID=8YFLogxK
U2 - 10.1016/j.jconrel.2006.09.070
DO - 10.1016/j.jconrel.2006.09.070
M3 - Article
C2 - 17718994
AN - SCOPUS:34548730854
SN - 0168-3659
VL - 116
SP - e98-e100
JO - Journal of Controlled Release
JF - Journal of Controlled Release
IS - 2
ER -