Partition coefficients of some aromatic alcohols in an n-heptane/water system and their relationship to minimum inhibitory concentration against Pseudomonas aeruginosa and Staphylococcus aureus

J. R J Wilson, J. Lyall, R. J. McBride

Research output: Contribution to journalArticle

Abstract

The partition coefficients of the homologous series of aromatic alcohols were determined in an n-heptane/water system. The minimum inhibitory concentrations of benzyl alcohol, 2-phenylethanol, 3-phenylpropanol, 4-phenylbutanol and 5-phenylpentanol were elucidated against Pseudomonas aeruginosa and Staphylococcus aureus. The linear relationship log 1/C = a log P+b postulated by Hansch was found to apply.

Original languageEnglish
Pages (from-to)63-66
Number of pages4
JournalJournal of Clinical and Hospital Pharmacy
Volume6
Issue number1
Publication statusPublished - 1981

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