Palladium-catalyzed direct C-H functionalization of benzoquinone

Sarah E. Walker, James A. Jordan-Hore, David G. Johnson, Stuart A. MacGregor, Ai Lan Lee

Research output: Contribution to journalArticle

106 Downloads (Pure)

Abstract

A direct Pd-catalyzed C-H functionalization of benzoquinone (BQ) can be controlled to give either mono- or disubstituted BQ, including the installation of two different groups in a one-pot procedure. BQ can now be directly functionalized with aryl, heteroaryl, cycloalkyl, and cyclo-alkene groups and, moreover, the reaction is conducted in environmentally benign water or acetone as solvents.

Original languageEnglish
Pages (from-to)13876-13879
Number of pages4
JournalAngewandte Chemie International Edition
Volume53
Issue number50
DOIs
Publication statusPublished - 10 Oct 2014

    Fingerprint

Keywords

  • Benzoquinone
  • C-H functionalization
  • Palladium
  • Synthetic methods
  • Water

Cite this