Optofluidic blood cell sorting

I. A. Andreev, A. C. Riches, T. Briscoe, L. Paterson, K. Dholakia, M. P. MacDonald

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Optofluidics is rapidly becoming an established part of the microfluidic toolkit, due in part to the ease with which an optofluidic device can be reconfigured. In this paper we describe how it is possible to sort blood cells by configuring an optically induced potential energy landscape within a microfluidic flow to selectively deflect erythrocytes. When transported within an isotonic buffer, blood cells can be sorted according to their shape. Alternatively, by placing the cells in a hypotonic buffer, erythrocytes can be spherised and sorting can be accomplished according to size.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages470-472
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - 2007
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2007 - Paris, France
Duration: 7 Oct 200711 Oct 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2007
Abbreviated titleuTAS 2007
Country/TerritoryFrance
CityParis
Period7/10/0711/10/07

Keywords

  • Blood
  • Cell sorting
  • Optical manipulation
  • Optofluidics

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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