Optical fibre cantilever sensor for biological application

Ji Li, Y. X. Zhou, G. Patterson, W. M. Shu, R. R J Maier, R. Fowler, D. P. Hand, W. N. Macpherson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Micro-cantilever sensors have shown great promise in a wide range of application are as including chemical and biological sensing. However, many of these devices are based upon a sensor 'chip' that requires careful alignment between the cantilever and the read-out system, which can be challenging. Furthermore, optical interrogation typically involves a bulky free-space system. Optical fibre addressed cantilevers have been reported previously in the literature and in this paper we propose techniques to design and fabricate polymer micro-cantilevers for attachment onto the end of standard single mode fibres using laser machining. Low-cost optical sources and a fibre coupled spectrometer are employed to monitor the cantilever deflection and therefore observe biological binding between a species of interest and an activated cantilever. Proof-of-concept experiments show that the sensor is capable of detecting pathogen concentration with down to a level of 105cfu/ml.

Original languageEnglish
Title of host publication23rd International Conference on Optical Fibre Sensors
Place of PublicationBellingham
PublisherSPIE
Volume9157
ISBN (Print)9781628411751
DOIs
Publication statusPublished - 2014
Event23rd International Conference on Optical Fibre Sensors - Santander, United Kingdom
Duration: 2 Jun 20146 Jun 2014

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume9157
ISSN (Print)0277-786X

Conference

Conference23rd International Conference on Optical Fibre Sensors
CountryUnited Kingdom
CitySantander
Period2/06/146/06/14

Keywords

  • Laser fabrication
  • Micro-machining
  • Optical fibre cantilever
  • Pathogen detection

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Applied Mathematics
  • Computer Science Applications
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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  • Cite this

    Li, J., Zhou, Y. X., Patterson, G., Shu, W. M., Maier, R. R. J., Fowler, R., Hand, D. P., & Macpherson, W. N. (2014). Optical fibre cantilever sensor for biological application. In 23rd International Conference on Optical Fibre Sensors (Vol. 9157). [91575I] (Proceedings of SPIE; Vol. 9157). SPIE. https://doi.org/10.1117/12.2059869