On-chip production of nanometer sized 'Ultra fine' bubble populations

Sally A. Peyman; James McLaughlan; Gemma Marston; Steven Freear; P. Louise Coletta; Stephen D. Evans

On-chip production of nanometer sized 'Ultra fine' bubble populations

Sally A. Peyman, James McLaughlan, Gemma Marston, Steven Freear, P. Louise Coletta, Stephen D. Evans^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Microbubble (MB) contrast agents have been used for many years as image enhancers for medical Ultrasound (US). Ultra-Fine bubble (UFB) populations of bubbles <1 μm in diameter are a relatively new technology that has found use as highly effective 'eco' cleaning agents. High-resolution US imaging is another potentially exciting area for UFB. This paper reports the on-chip production of UFB populations with a diameter of ∼ 500-700 nm at a concentration of 10¹⁰ bub / mL. These UFB showed US scattering at higher frequency fields and enhanced contrast when imaging in in vivo mouse models.

Original language	English
Title of host publication	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014
Publisher	Chemical and Biological Microsystems Society
Pages	1244-1246
Number of pages	3
ISBN (Electronic)	9780979806476
Publication status	Published - 2014
Event	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014 - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014

Conference

Conference	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014
Abbreviated title	MicroTAS 2014
Country/Territory	United States
City	San Antonio
Period	26/10/14 → 30/10/14

Keywords

Contrast agents
Ultra-Fine bubbles
Ultra-Sound

ASJC Scopus subject areas

Control and Systems Engineering

Cite this

@inproceedings{a7e0532701b64e1cb3b69d67eb377a65,

title = "On-chip production of nanometer sized 'Ultra fine' bubble populations",

abstract = "Microbubble (MB) contrast agents have been used for many years as image enhancers for medical Ultrasound (US). Ultra-Fine bubble (UFB) populations of bubbles <1 μm in diameter are a relatively new technology that has found use as highly effective 'eco' cleaning agents. High-resolution US imaging is another potentially exciting area for UFB. This paper reports the on-chip production of UFB populations with a diameter of ∼ 500-700 nm at a concentration of 1010 bub / mL. These UFB showed US scattering at higher frequency fields and enhanced contrast when imaging in in vivo mouse models.",

keywords = "Contrast agents, Ultra-Fine bubbles, Ultra-Sound",

author = "Peyman, {Sally A.} and James McLaughlan and Gemma Marston and Steven Freear and Coletta, {P. Louise} and Evans, {Stephen D.}",

note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",

year = "2014",

language = "English",

pages = "1244--1246",

booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014",

publisher = "Chemical and Biological Microsystems Society",

}

Peyman, SA, McLaughlan, J, Marston, G, Freear, S, Coletta, PL & Evans, SD 2014, On-chip production of nanometer sized 'Ultra fine' bubble populations. in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014. Chemical and Biological Microsystems Society, pp. 1244-1246, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014, San Antonio, Texas, United States, 26/10/14.

On-chip production of nanometer sized 'Ultra fine' bubble populations. / Peyman, Sally A.; McLaughlan, James; Marston, Gemma et al.
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014. Chemical and Biological Microsystems Society, 2014. p. 1244-1246.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - On-chip production of nanometer sized 'Ultra fine' bubble populations

AU - Peyman, Sally A.

AU - McLaughlan, James

AU - Marston, Gemma

AU - Freear, Steven

AU - Coletta, P. Louise

AU - Evans, Stephen D.

PY - 2014

Y1 - 2014

N2 - Microbubble (MB) contrast agents have been used for many years as image enhancers for medical Ultrasound (US). Ultra-Fine bubble (UFB) populations of bubbles <1 μm in diameter are a relatively new technology that has found use as highly effective 'eco' cleaning agents. High-resolution US imaging is another potentially exciting area for UFB. This paper reports the on-chip production of UFB populations with a diameter of ∼ 500-700 nm at a concentration of 1010 bub / mL. These UFB showed US scattering at higher frequency fields and enhanced contrast when imaging in in vivo mouse models.

AB - Microbubble (MB) contrast agents have been used for many years as image enhancers for medical Ultrasound (US). Ultra-Fine bubble (UFB) populations of bubbles <1 μm in diameter are a relatively new technology that has found use as highly effective 'eco' cleaning agents. High-resolution US imaging is another potentially exciting area for UFB. This paper reports the on-chip production of UFB populations with a diameter of ∼ 500-700 nm at a concentration of 1010 bub / mL. These UFB showed US scattering at higher frequency fields and enhanced contrast when imaging in in vivo mouse models.

KW - Contrast agents

KW - Ultra-Fine bubbles

KW - Ultra-Sound

UR - http://www.scopus.com/inward/record.url?scp=84941711427&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84941711427

SP - 1244

EP - 1246

BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014

PB - Chemical and Biological Microsystems Society

T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2014

Y2 - 26 October 2014 through 30 October 2014

ER -

On-chip production of nanometer sized 'Ultra fine' bubble populations

Abstract

Conference

Keywords

ASJC Scopus subject areas

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