Novel optical technologies for ultrashort pulsed laser surgery

Donald R. Risbridger, Rainer J. Beck, Syam P. C. Mohanan, Aongus McCarthy, Mike Shires, David Jayne, Jonathan D. Shephard

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Abstract

Colorectal cancer is the fourth-most prominent cause of cancer related fatalities across the globe. Conventional electrocautery techniques used in the resection of colon tissue cause a relatively high degree of collateral damage to the healthy tissues bordering the target sites. Ultrafast infrared lasers offer significantly improved localisation in the ablation of such biological tissues arising from a plasma-mediated ablation mechanism. This improved localisation is two-fold, with lateral confinement and precise depth control being advantageous in minimising thermal necrosis and avoiding bowel perforation respectively. Various laser scanning strategies and optical elements have been investigated, with the intent to exploit the inherent advantages offered from applying photonics to these procedures. Evaluation of the corresponding ablation characteristics was carried out using three-dimensional optical profilometry and histological analysis. If adopted in operating theatres, surgeons could benefit from more control when carrying out resection of neoplasia in the mucosal or submucosal layers of colon tissue, compared to previous electrocautery methods.

Original languageEnglish
Title of host publicationNovel Biophotonics Techniques and Applications V
EditorsArjen Amelink, Seemantini K. Nadkarni
PublisherSPIE
ISBN (Electronic)9781510628441
ISBN (Print)9781510628434
DOIs
Publication statusPublished - 22 Jul 2019
EventEuropean Conferences on Biomedical Optics 2019 - Munich, Germany
Duration: 26 Jun 201927 Jun 2019

Publication series

NameProceedings of SPIE
Volume11075
ISSN (Print)1605-7422
ISSN (Electronic)2410-9045

Conference

ConferenceEuropean Conferences on Biomedical Optics 2019
CountryGermany
CityMunich
Period26/06/1927/06/19

Keywords

  • cancer.
  • fibre delivery
  • infrared
  • laser
  • laser surgery
  • plasma-mediated ablation
  • tissue
  • Ultrafast

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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