Molecular interactions in collagen and chitosan blends

Alina Sionkowska, M Wisniewski, J Skopinska, Craig J Kennedy, Timothy J Wess

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    Abstract

    Molecular interactions between collagen and chitosan (CC) have the potential to produce biocomposites with novel properties.
    We have characterised the molecular interactions in CC complexes by viscometry, wide angle X-ray scattering and Fourier
    transform infrared spectroscopy. It was found that CC are miscible at the molecular level and exhibit interactions between the
    components; X-ray diffraction of CC blends indicate that the collagen helix structure is lost in CC films with increasing chitosan
    content. Non-linear viscometic behaviour with decreasing chitosan content is interpreted as evidence of a third structural phase
    formed as a complex of CC. The blending of collagen with chitosan gives the possibility of producing new bespoke materials for
    potential biomedical applications.
    Original languageEnglish
    Pages (from-to)795-801
    Number of pages7
    JournalBiomaterials
    Volume25
    Issue number5
    DOIs
    Publication statusPublished - Feb 2004

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    Sionkowska, A., Wisniewski, M., Skopinska, J., Kennedy, C. J., & Wess, T. J. (2004). Molecular interactions in collagen and chitosan blends. Biomaterials, 25(5), 795-801. https://doi.org/10.1016/S0142-9612(03)00595-7