Molecular interactions in collagen and chitosan blends

Alina Sionkowska, M Wisniewski, J Skopinska, Craig J Kennedy, Timothy J Wess

    Research output: Contribution to journalArticlepeer-review

    453 Citations (Scopus)


    Molecular interactions between collagen and chitosan (CC) have the potential to produce biocomposites with novel properties.
    We have characterised the molecular interactions in CC complexes by viscometry, wide angle X-ray scattering and Fourier
    transform infrared spectroscopy. It was found that CC are miscible at the molecular level and exhibit interactions between the
    components; X-ray diffraction of CC blends indicate that the collagen helix structure is lost in CC films with increasing chitosan
    content. Non-linear viscometic behaviour with decreasing chitosan content is interpreted as evidence of a third structural phase
    formed as a complex of CC. The blending of collagen with chitosan gives the possibility of producing new bespoke materials for
    potential biomedical applications.
    Original languageEnglish
    Pages (from-to)795-801
    Number of pages7
    Issue number5
    Publication statusPublished - Feb 2004


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