Modified Composite Nanomaterials as Novel Approach to Dental Hygiene Formulation

Marah Mazen Mahmoud, Muhammad Ashraf Sabri, Elias Djilali, Taleb H. Ibrahim, Mustafa I. Khamis, Sarah Dalibalta, Ruqaiyyah Siddiqui, Naveed Ahmed Khan

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Oral care and dental hygiene are integral parts of self-care. In the past few decades, there has been increased development in mouthwashes as oral care products. However, existing products maylead to a dry mouth or rely on ethanol. Herein, for the first time, we investigated the antibacterial effects of cetylpyridinium chloride, a cationic surfactant, intercalated with montmorillonite, a smectite clay to form a cetylpyridinium chloride-montmorillonite clay complex. Antibacterial assays revealed that the complex was able to eradicate oral bacteria in human saliva within 2 minutes, at a concentration of 0.05g/L as determined by plating human saliva onto nutrient agar plates post-treatment. These are very encouraging findings that could improve mouthwash formulations to remove stains and plaque against various oral bacteria.
Original languageEnglish
Pages (from-to)3944-3953
Number of pages10
JournalLetters in Applied NanoBioscience
Issue number4
Early online date26 Oct 2021
Publication statusPublished - 2022


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