Model systems for flavoenzyme activity: Site-isolated redox behavior in flavin-functionalized random polystyrene copolymers

Joseph B. Carroll, Brian J. Jordan, Hao Xu, Belma Erdogan, Lisa Lee, Lily Cheng, Christopher Tiernan, Graeme Cooke, Vincent M. Rotello

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

A model system has been developed to study the redox behaviors of flavin derivatives appended onto random polystyrene copolymers through "click" chemistry strategies. The results demonstrate that flavin units attached onto polymers exhibit site-isolated redox behaviors, yielding new materials with electrochemically tunable associations (Ka(ox) = 450 M-1, Ka(red) = 18 200 M-1) to complementary diamidopyridine (DAP) functionality. © 2005 American Chemical Society.

Original languageEnglish
Pages (from-to)2551-2554
Number of pages4
JournalOrganic Letters
Volume7
Issue number13
DOIs
Publication statusPublished - 2005

Fingerprint Dive into the research topics of 'Model systems for flavoenzyme activity: Site-isolated redox behavior in flavin-functionalized random polystyrene copolymers'. Together they form a unique fingerprint.

  • Cite this

    Carroll, J. B., Jordan, B. J., Xu, H., Erdogan, B., Lee, L., Cheng, L., Tiernan, C., Cooke, G., & Rotello, V. M. (2005). Model systems for flavoenzyme activity: Site-isolated redox behavior in flavin-functionalized random polystyrene copolymers. Organic Letters, 7(13), 2551-2554. https://doi.org/10.1021/ol0505407